Progesterone

Also known as: Pregn-4-ene-3,20-dione, 4-Pregnen-3,20-dione, 4-Pregnene-3,20-dione, Progestin, Lutein, Luteol, Luteum, Lutex, Lutin, Gestiron, Gestron, Glanducorpin, Gynlutin, Gynoluton, Gynolutone, Lugesteron, Primolut, Progestogel, Progestol, Prontogest

Progesterone (CAS 57-83-0) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C21H30O2 and a molecular weight of 314.462 g/mol. Key properties include a melting point of 128-132 °C(lit.), a boiling point of 447.2±45.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 166.7±25.7 °C. It is classified under GHS with signal word Warning and hazard statements H351 — Suspected of causing cancer and H361 — Suspected of damaging fertility or the unborn child. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 57-83-0
Jingsj CID: J-44229-1
Molecular Formula: C₂₁H₃₀O₂
Molecular Weight: 314.462 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	128-132 °C(lit.)
Boiling Point	447.2±45.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	166.7±25.7 °C
Exact Mass	314.224579
PSA	34.14000
LogP	4.04
Vapor Pressure	0.0±1.1 mmHg at 25°C
Refractive Index	1.542

GHS Safety & Compliance

Health HazardSignal word: Warning

H351 — Suspected of causing cancer
H361 — Suspected of damaging fertility or the unborn child

Activity & Biological Data

Target	Human Endogenous Metabolite
Additional Information	[1]. Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2003 Dec 10;46 Suppl 1:S7-S16. [2]. Zava DT, et al. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med. 1998 Mar;217(3):369-78. [3]. Komesaroff PA, et al. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001 Jun;4(2):144-50.

Target

Human Endogenous Metabolite

Additional Information

[1]. Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2003 Dec 10;46 Suppl 1:S7-S16. [2]. Zava DT, et al. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med. 1998 Mar;217(3):369-78. [3]. Komesaroff PA, et al. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001 Jun;4(2):144-50.

Frequently Asked Questions

What is the CAS number of Progesterone?

The CAS number of Progesterone is 57-83-0.

What are the molecular formula and molecular weight of Progesterone?

Progesterone has molecular formula C21H30O2 and molecular weight 314.462 g/mol.

Is Progesterone hazardous?

Progesterone has GHS signal word Warning and hazard statements H351 — Suspected of causing cancer; H361 — Suspected of damaging fertility or the unborn child.

What are the upstream and downstream products of Progesterone?

For Progesterone, Upstream Products: 16-Dehydroprogesterone, Deoxycorticosterone, Pregnenolone; Downstream Products: 5α-Dihydroprogesterone, Allopregnanolone, 20α-Hydroxyprogesterone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Progesterone (CAS 57-83-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-44229-1 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.