Valrubicin

戊柔比星

Also known as: AD32, N-Trifluoroacetyladriamycin 14-valerate, N-Trifluoroacetyldoxorubicin 14-valerate, N-trifluoroacetyladriamycin-14-valerate, N-trifluoroacetyldoxorubicin-14-valerate, Valstar, antibiotic AD32, NSC-246131, trifluoroacetyladriamycin-14-valerate, trifluoroacetyl-adriamycin14-valerate, Pentanoic acid, 2-[(2S,4S)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-[(2,2,2-trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-2-naphthacenyl]-2-oxoethyl ester, 2-Oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-({2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl}oxy)-1,2,3,4,6,11-hexahydrotetracen-2-yl]ethyl pentanoate, 2-oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-({2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl}oxy)-1,2,3,4,6,11-hexahydrotetracen-2-yl]ethyl valerate

Valrubicin (CAS 56124-62-0) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C34H36F3NO13 and a molecular weight of 723.644 g/mol. It is also known as AD32, N-Trifluoroacetyladriamycin 14-valerate and N-Trifluoroacetyldoxorubicin 14-valerate. Key properties include a melting point of 116-117ºC, a boiling point of 867.7±65.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 478.6±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 56124-62-0
Jingsj CID: J-1316386-8
Molecular Formula: C₃₄H₃₆F₃NO₁₃
Chinese Name: 戊柔比星
Molecular Weight: 723.644 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	116-117ºC
Boiling Point	867.7±65.0 °C at 760 mmHg
Density	1.5±0.1 g/cm3
Flash Point	478.6±34.3 °C
Exact Mass	723.213867
PSA	215.22000
LogP	6.31
Vapor Pressure	0.0±0.3 mmHg at 25°C
Refractive Index	1.619
Storage Conditions	2-8℃
Additional Property	insoluble

Activity & Biological Data

Target	TPA-activated PKC:0.85 μM (IC50) PDBu-activated PKC:1.25 μM (IC50)
Additional Information	[1]. Chuang LF, et al. Activation of human leukemia protein kinase C by tumor promoters and its inhibition by N-trifluoroacetyladriamycin-14-valerate (AD 32). Biochem Pharmacol. 1992 Feb 18;43(4):865-72. [2]. Wani MK, et al. Rationale for intralesional valrubicin in chemoradiation of squamous cell carcinoma of the head and neck. Laryngoscope. 2000 Dec;110(12):2026-32. [3]. Hauge E, et al. Topical valrubicin application reduces skin inflammation in murine models. Br J Dermatol. 2012 Aug;167(2):288-95.

Target

TPA-activated PKC:0.85 μM (IC50) PDBu-activated PKC:1.25 μM (IC50)

Additional Information

[1]. Chuang LF, et al. Activation of human leukemia protein kinase C by tumor promoters and its inhibition by N-trifluoroacetyladriamycin-14-valerate (AD 32). Biochem Pharmacol. 1992 Feb 18;43(4):865-72. [2]. Wani MK, et al. Rationale for intralesional valrubicin in chemoradiation of squamous cell carcinoma of the head and neck. Laryngoscope. 2000 Dec;110(12):2026-32. [3]. Hauge E, et al. Topical valrubicin application reduces skin inflammation in murine models. Br J Dermatol. 2012 Aug;167(2):288-95.

Frequently Asked Questions

What is the CAS number of Valrubicin?

The CAS number of Valrubicin is 56124-62-0.

What are the molecular formula and molecular weight of Valrubicin?

Valrubicin has molecular formula C34H36F3NO13 and molecular weight 723.644 g/mol.

What are the upstream and downstream products of Valrubicin?

For Valrubicin, Upstream Products: Vinyl valerate.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Valrubicin (CAS 56124-62-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1316386-8 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.