Homogentisic acid
Also known as: 2,5-Dihydroxyphenylacetic acid, 2,5-Dihydroxy-α-toluic acid, (2,5-Dihydroxyphenyl)acetic acid, 2-(2,5-Dihydroxyphenyl)acetic acid, Alcapton, Melanic acid, Homogentisinic acid, 2,5-Dihydroxybenzeneacetic acid, Benzeneacetic acid, 2,5-dihydroxy-
Homogentisic acid (CAS 451-13-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C8H8O4 and a molecular weight of 168.147 g/mol. Key properties include a melting point of 150-152 °C(lit.), a boiling point of 439.3±30.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 233.6±21.1 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. It is listed by 1 supplier, from 586.80 to 960.00 CNY. Record last updated Aug 21, 2026.
- CAS No.
- 451-13-8
- Jingsj CID
- J-28572-4
- Molecular Formula
- C8H8O4
- Molecular Weight
- 168.147 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
| Supplier | Purity / Pack | Base Price | Unit Price | Origin | |
|---|---|---|---|---|---|
In Stock | >95.0%(T) 5g | ¥2,934.00 | $87.81 /gBest ¥586.80/g CNY | CN China MOQ 5g | |
In Stock | ≥97.0%(T) 5g | ¥2,934.00 | $87.81 /g ¥586.80/g CNY | CN China MOQ 5g | |
In Stock | >95.0%(T) 1g | ¥960.00 | $143.66 /g ¥960.00/g CNY | CN China MOQ 1g |
Physicochemical Properties
| Melting Point | 150-152 °C(lit.) |
|---|---|
| Boiling Point | 439.3±30.0 °C at 760 mmHg |
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 233.6±21.1 °C |
| Exact Mass | 168.042252 |
| PSA | 77.76000 |
| LogP | -0.07 |
| Appearance | crystalline | off-white to tan |
| Vapor Pressure | 0.0±1.1 mmHg at 25°C |
| Refractive Index | 1.643 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | Human Endogenous Metabolite |
|---|---|
| Additional Information | [1]. Öztekin N, et al. Determination of homogentisic acid in urine for diagnosis of alcaptonuria: Capillary electrophoretic method optimization using experimental design. Biomed Chromatogr. 2018 Jul;32(7):e4216. |
Customs & Trade Information
| HS Code | 2918290000 |
|---|---|
| Summary | HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Homogentisic acid?
The CAS number of Homogentisic acid is 451-13-8.
What are the molecular formula and molecular weight of Homogentisic acid?
Homogentisic acid has molecular formula C8H8O4 and molecular weight 168.147 g/mol.
Which suppliers offer Homogentisic acid?
1 supplier(s) listed; reference unit price ¥586.80–960.00 /g.
Is Homogentisic acid hazardous?
Homogentisic acid has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Homogentisic acid?
For Homogentisic acid, Upstream Products: (2,5-Dimethoxyphenyl)acetic acid, 1,4-Benzoquinone, Homogentisic acid gamma-lactone; Downstream Products: 2,5-Dihydroxybenzoic acid, Hydroquinone, Homogentisic acid gamma-lactone.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Homogentisic acid (CAS 451-13-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-28572-4 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.