Clonidine hydrochloride
Also known as: 2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride, 2-(2,6-Dichlorophenylamino)-2-imidazoline hydrochloride, 2,6-Dichloro-N-(imidazolidin-2-ylidene)aniline hydrochloride (1:1), 2,6-Dichloro-N-2-imidazolidinylidenebenzenamine Monohydrochloride, Catapres, Catapressan, Clonidine HCl, Clonidine monohydrochloride, Clonistada, Dixarit, Duraclon, Isoglaucon, N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride (1:1), Neuclon, Tenso-Timelets, atensina, capresin, clofelin, clonidine hydrochloride salt, dcai
Clonidine hydrochloride (CAS 4205-91-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C9H10Cl3N3 and a molecular weight of 266.555 g/mol. Key properties include a melting point of 312 °C, a boiling point of 319.3ºC at760mmHg and a flash point of 146.9ºC. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed and H330 — Fatal if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 4205-91-8
- Jingsj CID
- J-19622-5
- Molecular Formula
- C9H10Cl3N3
- Molecular Weight
- 266.555 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 312 °C |
|---|---|
| Boiling Point | 319.3ºC at760mmHg |
| Flash Point | 146.9ºC |
| Exact Mass | 264.994019 |
| PSA | 36.42000 |
| LogP | 3.00390 |
| Additional Property | H2O: 50 mg/mL, clear, colorless |
GHS Safety & Compliance
- H301 — Toxic if swallowed
- H330 — Fatal if inhaled
Activity & Biological Data
| Additional Information | [1]. Bugajski J, et al. The involvement of central alpha-adrenergic and histamine H2-receptors in the hypothermia induced by clonidine in the rat. Neuropharmacology. 1980 Jan;19(1):9-15. [2]. Zhang YM, et al. Clonidine induces calcitonin gene-related peptide expression via nitric oxide pathway in endothelial cells. Peptides. 2009 Sep;30(9):1746-52. [3]. Jentsch JD, et al. Clonidine and guanfacine attenuate phencyclidine-induced dopamine overflow in rat prefrontal cortex: mediating influence of the alpha-2A adrenoceptor subtype. Brain Res. 2008 Dec 30;1246:41-6. [4]. Nassar N, et al. Brainstem adenosine A1 receptor signaling masks phosphorylated extracellular signal-regulated kinase 1/2-dependent hypotensive action of clonidine in conscious normotensive rats. J Pharmacol Exp Ther. 2009 Jan;328(1):83-9. |
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Customs & Trade Information
| HS Code | 2933290090 |
|---|---|
| Summary | 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Clonidine hydrochloride?
The CAS number of Clonidine hydrochloride is 4205-91-8.
What are the molecular formula and molecular weight of Clonidine hydrochloride?
Clonidine hydrochloride has molecular formula C9H10Cl3N3 and molecular weight 266.555 g/mol.
Is Clonidine hydrochloride hazardous?
Clonidine hydrochloride has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H330 — Fatal if inhaled.
What are the upstream and downstream products of Clonidine hydrochloride?
For Clonidine hydrochloride, Upstream Products: 2,6-Dichloroaniline, 1-Acetylimidazolidin-2-one, 2-Imidazolidone.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Clonidine hydrochloride (CAS 4205-91-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-19622-5 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.