Auranofin

金诺芬

Also known as: Auranofine, Ridaura, SKF-39162, SK&F 39162, Adtil, Crisinor, Crisofin, Ridauran, Auranon, (2,3,4,6-Tetra-O-acetyl-1-thio-β-L-glucopyranosato-κS)(triethylphosphoranylidene)gold, Gold, (1-thio-β-D-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-, (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate

Auranofin (CAS 34031-32-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H36AuO9PS and a molecular weight of 680.50 g/mol. It is also known as Auranofine, Ridaura and SKF-39162. Key properties include a melting point of 103 - 105ºC, a boiling point of 425.5ºC at 760mmHg and a flash point of 298ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 34031-32-8
Jingsj CID: J-45290-0
Molecular Formula: C₂₀H₃₆AuO₉PS
Chinese Name: 金诺芬
Molecular Weight: 680.50 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	103 - 105ºC
Boiling Point	425.5ºC at 760mmHg
Flash Point	298ºC
PSA	149.54000
LogP	2.79250
Additional Property	DMSO: ≥5mg/mL

Activity & Biological Data

Target	IC50: 0.2 μM (TrxR)[1]
Additional Information	[1]. Cox AG, et al. The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation. Biochem Pharmacol. 2008 Oct 30;76(9):1097-109. [2]. Park SH, et al. Auranofin displays anticancer activity against ovarian cancer cells through FOXO3 activation independent of p53. Int J Oncol. 2014 Oct;45(4):1691-8. [3]. Park N, et al. Auranofin promotes mitochondrial apoptosis by inducing annexin A5 expression and translocation in human prostate cancer cells. J Toxicol Environ Health A. 2014;77(22-24):1467-76. [4]. Lee JC, et al. Effect of auranofin treatment on aberrant splenic interleukin production in adjuvant arthritic rats. J Immunol. 1987 Nov 15;139(10):3268-74.

Target

IC50: 0.2 μM (TrxR)[1]

Additional Information

[1]. Cox AG, et al. The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation. Biochem Pharmacol. 2008 Oct 30;76(9):1097-109. [2]. Park SH, et al. Auranofin displays anticancer activity against ovarian cancer cells through FOXO3 activation independent of p53. Int J Oncol. 2014 Oct;45(4):1691-8. [3]. Park N, et al. Auranofin promotes mitochondrial apoptosis by inducing annexin A5 expression and translocation in human prostate cancer cells. J Toxicol Environ Health A. 2014;77(22-24):1467-76. [4]. Lee JC, et al. Effect of auranofin treatment on aberrant splenic interleukin production in adjuvant arthritic rats. J Immunol. 1987 Nov 15;139(10):3268-74.

Frequently Asked Questions

What is the CAS number of Auranofin?

The CAS number of Auranofin is 34031-32-8.

What are the molecular formula and molecular weight of Auranofin?

Auranofin has molecular formula C20H36AuO9PS and molecular weight 680.50 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Auranofin (CAS 34031-32-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-45290-0 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.