Azaphen hydrochloride

阿扎吩

Also known as: Azaphen, Pipofezine hydrochloride, Pipofezin hydrochloride, 5-Methyl-3-(4-methylpiperazin-1-yl)-5H-pyridazino[3,4-b][1,4]benzoxazine dihydrochloride, 5-Methyl-3-(4-methyl-1-piperazinyl)-5H-pyridazino(3,4-b)(1,4)benzoxazine dihydrochloride, Azafen, Azaphen (Pipofezine), Azaphenonxazine

Azaphen hydrochloride (CAS 24853-80-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H21Cl2N5O and a molecular weight of 370.27700 g/mol. It is also known as Azaphen, Pipofezine hydrochloride and Pipofezin hydrochloride. Key properties include a boiling point of 536ºC at 760 mmHg and a flash point of 278ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 24853-80-3
Jingsj CID: J-1981486-7
Molecular Formula: C₁₆H₂₁Cl₂N₅O
Chinese Name: 阿扎吩
Molecular Weight: 370.27700 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	536ºC at 760 mmHg
Flash Point	278ºC
Exact Mass	369.11200
PSA	44.73000
LogP	3.77390
Vapor Pressure	1.46E-11mmHg at 25°C

Activity & Biological Data

Additional Information	[1]. Domestic antidepressants. 1. Azaphen By Andreeva, N. I.; Asnina, V. V.; Liberman, S. S. From Pharmaceutical Chemistry Journal (Translation of Khimiko-Farmatsevticheskii Zhurnal) (2000), 34(5), 237-241. [2]. Shinaev NN, Akzhigitov RG. Azaphen: a return to clinical practice.Zh Nevrol Psikhiatr Im S S Korsakova. 2005;105(10):55-6. [3]. Ignatowicz L, Ignatowicz R, Wdowiak MW, Jaremko A. Azaphen in the treatment of enuresis in children.Psychiatr Pol. 1977 Jan-Feb;11(1):29-33. [4]. Liberman SS, Sharova SA. A comparison of the effect of the tricyclic antidepressants azaphen and imizin on the gastrointestinal tracts of experimental animals.Farmakol Toksikol. 1975 Jan-Feb;38(1):29-32. [5]. Misurec J, Náhunek K, Kamenická V, Chmelar M. Proceedings: Influence of azaphen, a new antidepressive drug, on the human EEG. Act Nerv Super (Praha). 1974;16(4):245-6.

Additional Information

[1]. Domestic antidepressants. 1. Azaphen By Andreeva, N. I.; Asnina, V. V.; Liberman, S. S. From Pharmaceutical Chemistry Journal (Translation of Khimiko-Farmatsevticheskii Zhurnal) (2000), 34(5), 237-241. [2]. Shinaev NN, Akzhigitov RG. Azaphen: a return to clinical practice.Zh Nevrol Psikhiatr Im S S Korsakova. 2005;105(10):55-6. [3]. Ignatowicz L, Ignatowicz R, Wdowiak MW, Jaremko A. Azaphen in the treatment of enuresis in children.Psychiatr Pol. 1977 Jan-Feb;11(1):29-33. [4]. Liberman SS, Sharova SA. A comparison of the effect of the tricyclic antidepressants azaphen and imizin on the gastrointestinal tracts of experimental animals.Farmakol Toksikol. 1975 Jan-Feb;38(1):29-32. [5]. Misurec J, Náhunek K, Kamenická V, Chmelar M. Proceedings: Influence of azaphen, a new antidepressive drug, on the human EEG. Act Nerv Super (Praha). 1974;16(4):245-6.

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Azaphen hydrochloride?

The CAS number of Azaphen hydrochloride is 24853-80-3.

What are the molecular formula and molecular weight of Azaphen hydrochloride?

Azaphen hydrochloride has molecular formula C16H21Cl2N5O and molecular weight 370.27700 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Azaphen hydrochloride (CAS 24853-80-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1981486-7 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.