GW9662
2-氯-5-硝基-N-苯基苯酰胺
Also known as: 2-chloro-5-nitro-N-phenylbenzamide, 2-chloro-5-nitrobenzanilide, GW 9662, GW-9662, CS-762, MFCD01215270, TIMTEC-BB SBB006523
GW9662 (CAS 22978-25-2) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C13H9ClN2O3 and a molecular weight of 276.675 g/mol. It is also known as 2-chloro-5-nitro-N-phenylbenzamide, 2-chloro-5-nitrobenzanilide and GW 9662. Key properties include a melting point of 171-175 °C(lit.), a boiling point of 360.9±32.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 172.0±25.1 °C. It is classified under GHS with signal word Warning and hazard statements H317 — May cause an allergic skin reaction and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 22978-25-2
- Jingsj CID
- J-28060-6
- Molecular Formula
- C13H9ClN2O3
- Chinese Name
- 2-氯-5-硝基-N-苯基苯酰胺
- Molecular Weight
- 276.675 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 171-175 °C(lit.) |
|---|---|
| Boiling Point | 360.9±32.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 172.0±25.1 °C |
| Exact Mass | 276.030182 |
| PSA | 74.92000 |
| LogP | 2.76 |
| Appearance | solid | white |
| Vapor Pressure | 0.0±0.8 mmHg at 25°C |
| Refractive Index | 1.676 |
| Storage Conditions | 2-8℃ |
| Additional Property | DMSO: 26 mg/mL, soluble |
GHS Safety & Compliance
- H317 — May cause an allergic skin reaction
- H319 — Causes serious eye irritation
Activity & Biological Data
| Target | PPARγ:3.3 nM (IC50) PPARα:32 nM (IC50) PPARδ:2000 nM (IC50) |
|---|---|
| Additional Information | [1]. Leesnitzer LM, et al. Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662. Biochemistry. 2002 May 28;41(21):6640-50. [2]. Seargent JM, et al. GW9662, a potent antagonist of PPARgamma, inhibits growth of breast tumour cells and promotes the anticancer effects of the PPARgamma agonist rosiglitazone, independently of PPARgamma activation. Br J Pharmacol. 2004 Dec;143(8):933-7. [3]. Sato K, et al. PPARγ antagonist attenuates mouse immune-mediated bone marrow failure by inhibition of T cell function.Haematologica. 2016 Jan;101(1):57-67. [4]. Collino M, et al. The selective PPARgamma antagonist GW9662 reverses the protection of LPS in a model of renal ischemia-reperfusion. Kidney Int. 2005 Aug;68(2):529-36. |
Customs & Trade Information
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of GW9662?
The CAS number of GW9662 is 22978-25-2.
What are the molecular formula and molecular weight of GW9662?
GW9662 has molecular formula C13H9ClN2O3 and molecular weight 276.675 g/mol.
Is GW9662 hazardous?
GW9662 has GHS signal word Warning and hazard statements H317 — May cause an allergic skin reaction; H319 — Causes serious eye irritation.
What are the upstream and downstream products of GW9662?
For GW9662, Upstream Products: 2-Chloro-5-nitrobenzoyl chloride, 2-Chloro-5-nitrobenzoic acid.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "GW9662 (CAS 22978-25-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-28060-6 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.