3,4',5-Trimethoxy-trans-stilbene

3,4',5-三甲氧基-反-二苯代乙烯

Also known as: Trimethoxystilbene, Resveratrol trimethyl ether, E-Resveratrol Trimethyl Ether, Tri-O-methylresveratrol, Trans-Trimethoxyresveratrol, 1,3-dimethoxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]benzene, 3,5,4'-Trimethoxystilbene, methylated trans-resveratrol, O-permethylated E-resveratrol, TRISMETHOXYRESVERATROL

3,4',5-Trimethoxy-trans-stilbene (CAS 22255-22-7) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C17H18O3 and a molecular weight of 270.323 g/mol. It is also known as Trimethoxystilbene, Resveratrol trimethyl ether and E-Resveratrol Trimethyl Ether. Key properties include a melting point of 57ºC, a boiling point of 423.8±35.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 144.4±23.2 °C. It is classified under GHS with signal word Danger and hazard statements H315 — Causes skin irritation, H318 — Causes serious eye damage and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
22255-22-7
Jingsj CID
J-33938-6
Molecular Formula
C17H18O3
Chinese Name
3,4',5-三甲氧基-反-二苯代乙烯
Molecular Weight
270.323 g/mol
Category
Aromatic Hydrocarbons
Last updated
8/21/2026

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point57ºC
Boiling Point423.8±35.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point144.4±23.2 °C
Exact Mass270.125580
PSA27.69000
LogP4.61
Vapor Pressure0.0±1.0 mmHg at 25°C
Refractive Index1.600
Additional PropertyDMSO: ≥34mg/mL

GHS Safety & Compliance

Corrosion / Irritant / Environmental HazardSignal word: Danger
  • H315 — Causes skin irritation
  • H318 — Causes serious eye damage
  • H335 — May cause respiratory irritation
  • H410 — Very toxic to aquatic life with long lasting effects

Activity & Biological Data

Additional Information[1]. Alex, D. et al. Resveratrol derivative, trans-3,5,4'-trimethoxystilbene, exerts antiangiogenic and vascular-disrupting effects in zebrafish through the downregulation of VEGFR2 and cell-cycle modulation. Journal of cellular biochemistry 109, 339-346, doi:

Customs & Trade Information

HS Code2909309090
Summary2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 3,4',5-Trimethoxy-trans-stilbene?

The CAS number of 3,4',5-Trimethoxy-trans-stilbene is 22255-22-7.

What are the molecular formula and molecular weight of 3,4',5-Trimethoxy-trans-stilbene?

3,4',5-Trimethoxy-trans-stilbene has molecular formula C17H18O3 and molecular weight 270.323 g/mol.

Is 3,4',5-Trimethoxy-trans-stilbene hazardous?

3,4',5-Trimethoxy-trans-stilbene has GHS signal word Danger and hazard statements H315 — Causes skin irritation; H318 — Causes serious eye damage; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 3,4',5-Trimethoxy-trans-stilbene?

For 3,4',5-Trimethoxy-trans-stilbene, Upstream Products: 4-Methoxybenzaldehyde, 3,5-Dimethoxybenzaldehyde, Diethyl (4-methoxybenzyl)phosphonate; Downstream Products: Resveratrol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "3,4',5-Trimethoxy-trans-stilbene (CAS 22255-22-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-33938-6 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.