Hydrocortisone hemisuccinate

氢化可的松琥珀酸酯

Also known as: Hydrocortisone 21-hemisuccinate, Hydrocortisone 21-(hydrogen succinate), Cortisol 21-hemisuccinate, Cortisol hemisuccinate, Cortisol, 21-(hydrogen succinate), Hydrocortisone succinate, Hydrocortisone hydrogen succinate, saxizon

Hydrocortisone hemisuccinate (CAS 2203-97-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C25H34O8 and a molecular weight of 462.533 g/mol. It is also known as Hydrocortisone 21-hemisuccinate, Hydrocortisone 21-(hydrogen succinate) and Cortisol 21-hemisuccinate. Key properties include a boiling point of 685.5±55.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 231.1±25.0 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 2203-97-6
Jingsj CID: J-15080-4
Molecular Formula: C₂₅H₃₄O₈
Chinese Name: 氢化可的松琥珀酸酯
Molecular Weight: 462.533 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	685.5±55.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	231.1±25.0 °C
Exact Mass	462.225372
PSA	138.20000
LogP	2.13
Vapor Pressure	0.0±4.8 mmHg at 25°C
Refractive Index	1.587
Additional Property	Practically insoluble in water, freely soluble in acetone and in anhydrous ethanol. It dissolves in dilute solutions of alkali carbonates and alkali hydroxides.

Activity & Biological Data

Target	IL-6:6.7 μM (IC50) IL-3:21.4 μM (IC50)
Additional Information	[1]. Kang BS, et, al. Inhibitory effects of anti-inflammatory drugs on interleukin-6 bioactivity. Biol Pharm Bull. 2001 Jun;24(6):701-3. [2]. You YC, et, al. In vitro and in vivo application of pH-sensitive colon-targeting polysaccharide hydrogel used for ulcerative colitis therapy. Carbohydr Polym. 2015 Oct 5;130:243-53. [3]. Langhoff E, et, al. The immunosuppressive potency in vitro of physiological and synthetic steroids on lymphocyte cultures. Int J Immunopharmacol. 1987;9(4):469-73.

Target

IL-6:6.7 μM (IC50) IL-3:21.4 μM (IC50)

Additional Information

[1]. Kang BS, et, al. Inhibitory effects of anti-inflammatory drugs on interleukin-6 bioactivity. Biol Pharm Bull. 2001 Jun;24(6):701-3. [2]. You YC, et, al. In vitro and in vivo application of pH-sensitive colon-targeting polysaccharide hydrogel used for ulcerative colitis therapy. Carbohydr Polym. 2015 Oct 5;130:243-53. [3]. Langhoff E, et, al. The immunosuppressive potency in vitro of physiological and synthetic steroids on lymphocyte cultures. Int J Immunopharmacol. 1987;9(4):469-73.

Frequently Asked Questions

What is the CAS number of Hydrocortisone hemisuccinate?

The CAS number of Hydrocortisone hemisuccinate is 2203-97-6.

What are the molecular formula and molecular weight of Hydrocortisone hemisuccinate?

Hydrocortisone hemisuccinate has molecular formula C25H34O8 and molecular weight 462.533 g/mol.

What are the upstream and downstream products of Hydrocortisone hemisuccinate?

For Hydrocortisone hemisuccinate, Upstream Products: Succinic anhydride, Hydrocortisone; Downstream Products: Hydrocortisone.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Hydrocortisone hemisuccinate (CAS 2203-97-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-15080-4 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.