Riluzole
Also known as: 2-Amino-6-(trifluoromethoxy)benzothiazole, 2-Amino-6-(trifluoromethoxy)benzo[d]thiazole, 2-Amino-6-trifluoromethoxybenzothiazole, 2-Benzothiazolamine, 6-(trifluoromethoxy)-, 6-(Trifluoromethoxy)-1,3-benzothiazol-2-amine, 6-(Trifluoromethoxy)-2-benzothiazolamine, 6-(Trifluoromethoxy)benzo[d]thiazol-2-amine, 6-Trifluoromethoxy-benzothiazol-2-ylamine, 6-Trifluoromethoxybenzothiazole-2-yl-amine, Rilutek
Riluzole (CAS 1744-22-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C8H5F3N2OS and a molecular weight of 234.198 g/mol. Key properties include a melting point of 116-118ºC, a boiling point of 296.3±50.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 133.0±30.1 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 1744-22-5
- Jingsj CID
- J-33496-3
- Molecular Formula
- C8H5F3N2OS
- Molecular Weight
- 234.198 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 116-118ºC |
|---|---|
| Boiling Point | 296.3±50.0 °C at 760 mmHg |
| Density | 1.6±0.1 g/cm3 |
| Flash Point | 133.0±30.1 °C |
| Exact Mass | 234.007462 |
| PSA | 76.38000 |
| LogP | 2.84 |
| Vapor Pressure | 0.0±0.6 mmHg at 25°C |
| Refractive Index | 1.615 |
| Additional Property | DMSO: ≥25 mg/mL |
GHS Safety & Compliance
- H301 — Toxic if swallowed
Activity & Biological Data
| Target | Sodium channel[1] IC50: 43 μM (GABA receptor)[1] |
|---|---|
| Additional Information | [1]. He Y, et al. Neuroprotective agent riluzole potentiates postsynaptic GABA(A) receptor function. Neuropharmacology. 2002 Feb;42(2):199-209. [2]. Thompson JM, et al. Small-conductance calcium-activated potassium (SK) channels in the amygdala mediate pain-inhibiting effects of clinically available riluzole in a rat model of arthritis pain. Mol Pain. 2015 Aug 28;11:51. |
Customs & Trade Information
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Riluzole?
The CAS number of Riluzole is 1744-22-5.
What are the molecular formula and molecular weight of Riluzole?
Riluzole has molecular formula C8H5F3N2OS and molecular weight 234.198 g/mol.
Is Riluzole hazardous?
Riluzole has GHS signal word Danger and hazard statements H301 — Toxic if swallowed.
What are the upstream and downstream products of Riluzole?
For Riluzole, Upstream Products: 4-(Trifluoromethoxy)aniline, Potassium thiocyanate, Tetrabutylammonium thiocyanate; Downstream Products: 2-Chloro-6-(trifluoromethoxy)benzothiazole, 2-Hydrazono-6-(trifluoromethoxy)-2,3-dihydrobenzo[d]thiazole.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Riluzole (CAS 1744-22-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-33496-3 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.