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4-(Trifluoromethoxy)aniline

Also known as: p-Trifluoromethoxyaniline, 4-Trifluoromethoxyaniline, α,α,α-Trifluoro-p-anisidine, Riluzole Related Compound A, Benzenamine, 4-(trifluoromethoxy)-, p-Aminophenyl trifluoromethyl ether, MFCD00041314, EINECS 207-317-5

4-(Trifluoromethoxy)aniline (CAS 461-82-5) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C7H6F3NO and a molecular weight of 177.13 g/mol. Key properties include a boiling point of 192.4±0.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 80.6±0.0 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H310 and H315 — Causes skin irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
461-82-5
Jingsj CID
J-3161-8
Molecular Formula
C7H6F3NO
Molecular Weight
177.13 g/mol
Category
Organic Bases
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point192.4±0.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point80.6±0.0 °C
Exact Mass177.040146
PSA35.25000
LogP1.78
Vapor Pressure0.5±0.3 mmHg at 25°C
Refractive Index1.481

GHS Safety & Compliance

Corrosion / Acute Toxicity / Health HazardSignal word: Danger
  • H301 — Toxic if swallowed
  • H310
  • H315 — Causes skin irritation
  • H318 — Causes serious eye damage
  • H373 — May cause damage to organs through prolonged exposure

Customs & Trade Information

HS Code2922299090
Summary2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 4-(Trifluoromethoxy)aniline?

The CAS number of 4-(Trifluoromethoxy)aniline is 461-82-5.

What are the molecular formula and molecular weight of 4-(Trifluoromethoxy)aniline?

4-(Trifluoromethoxy)aniline has molecular formula C7H6F3NO and molecular weight 177.13 g/mol.

Is 4-(Trifluoromethoxy)aniline hazardous?

4-(Trifluoromethoxy)aniline has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H310; H315 — Causes skin irritation.

What are the upstream and downstream products of 4-(Trifluoromethoxy)aniline?

For 4-(Trifluoromethoxy)aniline, Upstream Products: 1-Nitro-4-(trifluoromethoxy)benzene, 1-Bromo-4-(trifluoromethoxy)benzene, 4-(Trifluoromethoxy)benzamide; Downstream Products: (Trifluoromethoxy)benzene, 4-(Trifluoromethoxy)phenyl isocyanate, FCCP.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "4-(Trifluoromethoxy)aniline (CAS 461-82-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-3161-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.