Ac-DEVD-CHO

Also known as: AC-DEVD-CHO, AC-DEVD-CHO?, >98%, Ac-DEVD-CHO,N-Acetyl-Asp-Glu-Val-Asp-al, >98%, CPP32/APOPAIN INHIBITOR, Caspase-3 Inhibitor I - CAS 169332-60-9 - Calbiochem, N-AC-ASP-GLU-VAL-ASP-CHO, N-ACETYL-ASP-GLU-VAL-ASP-AL, N-ACETYL-ASP-GLU-VAL-ASP-CHO (ALDEHYDE), N-ACETYL-L-ALPHA-ASPARTYL-L-ALPHA-GLUTAMYL-N-(2-CARBOXY-1-FORMYLETHYL)-L VALINAMIDE, N-Acetyl-Asp-Glu-Val-Asp-al, ac-devd-cho

Ac-DEVD-CHO (CAS 169332-60-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H30N4O11 and a molecular weight of 502.47200 g/mol. It is also known as AC-DEVD-CHO, AC-DEVD-CHO?, >98% and Ac-DEVD-CHO,N-Acetyl-Asp-Glu-Val-Asp-al, >98%. Key properties include a boiling point of 1021.1ºC at 760mmHg, a density of 1.374g/cm3 and a flash point of 571.3ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 169332-60-9
Jingsj CID: J-1962041-3
Molecular Formula: C₂₀H₃₀N₄O₁₁
Molecular Weight: 502.47200 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	1021.1ºC at 760mmHg
Density	1.374g/cm3
Flash Point	571.3ºC
Exact Mass	502.19100
PSA	245.37000
Vapor Pressure	0mmHg at 25°C
Refractive Index	1.535
Storage Conditions	-20°C

Activity & Biological Data

Target	Caspase 3:0.23 nM (Ki) Caspase-8:0.92 nM (Ki) Caspase-7:1.6 nM (Ki) Caspase-10:12 nM (Ki) Caspase-1:18 nM (Ki) Caspase-6:31 nM (Ki) Caspase-9:60 nM (Ki) Caspase-4:132 nM (Ki) Caspase-5:205 nM (Ki) Caspase-2:1710 nM (Ki)
Additional Information	[1]. Garcia-Calvo M, et al.nhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem. 1998 Dec 4;273(49):32608-13. [2]. Jinglin Wang, et al. A polysaccharide from Lentinus edodes inhibits human colon cancer cell proliferation and suppresses tumor growth in athymic nude mice. Oncotarget. 2017 Jan 3; 8(1): 610-623. [3]. Junping Zhang, et al. Hypericin-mediated photodynamic therapy induces apoptosis of myoloma SP2/0 cells depended on caspase activity in vitro. Cancer Cell Int. 2015; 15: 58 [4]. Long-gang He, et al. Sinomenine induces apoptosis in RAW 264.7 cell-derived osteoclasts in vitro via caspase-3 activation. Acta Pharmacol Sin. 2014 Feb; 35(2): 203-210. [5]. Liu LX, et al. The effect of caspase-3 inhibitor on the concentrations of serum inflammatory cytokines in sepsis related acute kidney injury induced by peritoneal cavity infection in mice. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2010 Dec;22(12):736-9.

Target

Caspase 3:0.23 nM (Ki) Caspase-8:0.92 nM (Ki) Caspase-7:1.6 nM (Ki) Caspase-10:12 nM (Ki) Caspase-1:18 nM (Ki) Caspase-6:31 nM (Ki) Caspase-9:60 nM (Ki) Caspase-4:132 nM (Ki) Caspase-5:205 nM (Ki) Caspase-2:1710 nM (Ki)

Additional Information

[1]. Garcia-Calvo M, et al.nhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem. 1998 Dec 4;273(49):32608-13. [2]. Jinglin Wang, et al. A polysaccharide from Lentinus edodes inhibits human colon cancer cell proliferation and suppresses tumor growth in athymic nude mice. Oncotarget. 2017 Jan 3; 8(1): 610-623. [3]. Junping Zhang, et al. Hypericin-mediated photodynamic therapy induces apoptosis of myoloma SP2/0 cells depended on caspase activity in vitro. Cancer Cell Int. 2015; 15: 58 [4]. Long-gang He, et al. Sinomenine induces apoptosis in RAW 264.7 cell-derived osteoclasts in vitro via caspase-3 activation. Acta Pharmacol Sin. 2014 Feb; 35(2): 203-210. [5]. Liu LX, et al. The effect of caspase-3 inhibitor on the concentrations of serum inflammatory cytokines in sepsis related acute kidney injury induced by peritoneal cavity infection in mice. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2010 Dec;22(12):736-9.

Frequently Asked Questions

What is the CAS number of Ac-DEVD-CHO?

The CAS number of Ac-DEVD-CHO is 169332-60-9.

What are the molecular formula and molecular weight of Ac-DEVD-CHO?

Ac-DEVD-CHO has molecular formula C20H30N4O11 and molecular weight 502.47200 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Ac-DEVD-CHO (CAS 169332-60-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1962041-3 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.