Levofloxacin hemihydrate

左氧氟沙星半水合物

Also known as: Levofloxacin hydrate, Levofloxacin heMihydrate, (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate, (S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid Hemihydrate, Levaquin, Cravit, Quixin, Iquix, Dynaquin, Levofloxacin (hemihydrate)

Levofloxacin hemihydrate (CAS 138199-71-0) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C18H20FN3O4.0.5H2O and a molecular weight of 370.38 g/mol. It is also known as Levofloxacin hydrate, Levofloxacin heMihydrate and (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate. Key properties include a melting point of 214-216°C, a boiling point of 571.5ºC at 760mmHg and a density of 1.48g/cm3. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed, H317 — May cause an allergic skin reaction and H334 — May cause allergy or asthma symptoms if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
138199-71-0
Jingsj CID
J-1114021-0
Molecular Formula
C18H20FN3O405H2O
Chinese Name
左氧氟沙星半水合物
Molecular Weight
370.38 g/mol
Category
Organohalogen Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point214-216°C
Boiling Point571.5ºC at 760mmHg
Density1.48g/cm3
PSA84.24000
LogP1.48260
Vapor Pressure6.7E-14mmHg at 25°C
Storage Conditions-20°C Freezer

GHS Safety & Compliance

Irritant / Health HazardSignal word: Danger
  • H302 — Harmful if swallowed
  • H317 — May cause an allergic skin reaction
  • H334 — May cause allergy or asthma symptoms if inhaled
  • H362

Activity & Biological Data

Additional Information[1]. Siva, R., et al., Effect of levofloxacin on neutrophilic airway inflammation in stable COPD: a randomized, double-blind, placebo-controlled trial. Int J Chron Obstruct Pulmon Dis, 2014. 9: p. 179-86. [2]. Pradeep, A.R., et al., Clinical and microbiological effects of levofloxacin in the treatment of chronic periodontitis: a randomized, placebo-controlled clinical trial. J Investig Clin Dent, 2014. [3]. Lee, B.T., et al., Efficacy of Levofloxacin in the Treatment of BK Viremia: A Multicenter, Double-Blinded, Randomized, Placebo-Controlled Trial. Clin J Am Soc Nephrol, 2014.

Frequently Asked Questions

What is the CAS number of Levofloxacin hemihydrate?

The CAS number of Levofloxacin hemihydrate is 138199-71-0.

What are the molecular formula and molecular weight of Levofloxacin hemihydrate?

Levofloxacin hemihydrate has molecular formula C18H20FN3O4.0.5H2O and molecular weight 370.38 g/mol.

Is Levofloxacin hemihydrate hazardous?

Levofloxacin hemihydrate has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H317 — May cause an allergic skin reaction; H334 — May cause allergy or asthma symptoms if inhaled.

What are the upstream and downstream products of Levofloxacin hemihydrate?

For Levofloxacin hemihydrate, Upstream Products: 1-Methylpiperazine, Levofloxacin carboxylic acid.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Levofloxacin hemihydrate (CAS 138199-71-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1114021-0 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.