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Doxepin hydrochloride

Also known as: 1-Propanamine, 3-dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride (1:1), 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz[b,e]oxepine hydrochloride, 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo[b,e]oxepine Hydrochloride, 3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethyl-1-propanamine hydrochloride (1:1), 3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine hydrochloride (1:1), 3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine hydrochloride, 3-Dibenzo[b,e]oxepin-11(6H)-yliden-N,N-dimethylpropan-1-aminhydrochlorid, Adapin, Curatin, Doxepin (Hydrochloride), N,N-Dimethyldibenz[b,e]oxepin-δ11(6H),γ-propylamine hydrochloride, Novoxapin, P 3693A, Quitaxon, doxepin HCl, MFCD00079135, EINECS 214-966-8

Doxepin hydrochloride (CAS 1229-29-4) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C19H22ClNO and a molecular weight of 315.837 g/mol. Key properties include a melting point of 187-189°C, a boiling point of 413.3ºC at 760mmHg and a flash point of 121.3ºC. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour, H301 — Toxic if swallowed and H311 — Toxic in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
1229-29-4
Jingsj CID
J-1984151-1
Molecular Formula
C19H22ClNO
Molecular Weight
315.837 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point187-189°C
Boiling Point413.3ºC at 760mmHg
Flash Point121.3ºC
Exact Mass315.138977
PSA12.47000
LogP4.76440
Vapor Pressure4.87E-07mmHg at 25°C
StabilityStore in Freezer at -20°C
Additional Property1 M HCl: 50 mg/mL

GHS Safety & Compliance

Flammable / Acute Toxicity / Health HazardSignal word: Danger
  • H225 — Highly flammable liquid and vapour
  • H301 — Toxic if swallowed
  • H311 — Toxic in contact with skin
  • H331 — Toxic if inhaled
  • H370 — Causes damage to organs

Activity & Biological Data

Additional Information[1]. http://pdsp.med.unc.edu/pdsp.php [2]. Hajak, G., et al., Doxepin in the treatment of primary insomnia: a placebo-controlled, double-blind, polysomnographic study. J Clin Psychiatry, 2001. 62(6): p. 453-63.

Customs & Trade Information

HS Code2932999099
Summary2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Doxepin hydrochloride?

The CAS number of Doxepin hydrochloride is 1229-29-4.

What are the molecular formula and molecular weight of Doxepin hydrochloride?

Doxepin hydrochloride has molecular formula C19H22ClNO and molecular weight 315.837 g/mol.

Is Doxepin hydrochloride hazardous?

Doxepin hydrochloride has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H301 — Toxic if swallowed; H311 — Toxic in contact with skin.

What are the upstream and downstream products of Doxepin hydrochloride?

For Doxepin hydrochloride, Upstream Products: 2-(Phenoxymethyl)benzoic acid, Sodium phenoxide, Ethyl 2-(bromomethyl)benzoate; Downstream Products: Dibenz[b,e]oxepin-11(6H)-one, Doxepin.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Doxepin hydrochloride (CAS 1229-29-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1984151-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.