Dosulepin
度硫平
Also known as: Dothiepin, (Z)-Dosulepin, Prothiaden, Altapin, Dothep, Methiaden, 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo[b,e]thiepin, 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine, Dosulepine, Dolsulepine, Prothiadene, EINECS 204-031-2
Dosulepin (CAS 113-53-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C19H21NS and a molecular weight of 295.44 g/mol. It is also known as Dothiepin, (Z)-Dosulepin and Prothiaden. Key properties include a melting point of 55-57ºC, a boiling point of 430.9±44.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 214.4±28.4 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 113-53-1
- Jingsj CID
- J-39577-1
- Molecular Formula
- C19H21NS
- Chinese Name
- 度硫平
- Molecular Weight
- 295.44 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 55-57ºC |
|---|---|
| Boiling Point | 430.9±44.0 °C at 760 mmHg |
| Density | 1.1±0.1 g/cm3 |
| Flash Point | 214.4±28.4 °C |
| Exact Mass | 295.139465 |
| PSA | 28.54000 |
| LogP | 4.34 |
| Vapor Pressure | 0.0±1.0 mmHg at 25°C |
| Refractive Index | 1.661 |
Activity & Biological Data
| Target | Histamine H1-receptor, Noradrenaline uptake (α1-and α2-adrenoceptors and serotonin 5HT1 and 5HT2-receptors)[1] |
|---|---|
| Additional Information | [1]. Lancaster SG, et al. Dothiepin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness. Drugs. 1989 Jul;38(1):123-47. |
Frequently Asked Questions
What is the CAS number of Dosulepin?
The CAS number of Dosulepin is 113-53-1.
What are the molecular formula and molecular weight of Dosulepin?
Dosulepin has molecular formula C19H21NS and molecular weight 295.44 g/mol.
What are the upstream and downstream products of Dosulepin?
For Dosulepin, Downstream Products: Dosulepin hydrochloride.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Dosulepin (CAS 113-53-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-39577-1 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.