Lazabemide hydrochloride

拉扎贝胺盐酸盐

Also known as: N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride, Lazabemide monohydrochloride, Ro 19-6327, Ro 19-6327/001, Tempium, 2-Pyridinecarboxamide, N-(2-aminoethyl)-5-chloro-, monohydrochloride

Lazabemide hydrochloride (CAS 103878-83-7) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C8H11Cl2N3O and a molecular weight of 236.09800 g/mol. It is also known as N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride, Lazabemide monohydrochloride and Ro 19-6327. Key properties include a boiling point of 397.4ºC at 760mmHg and a flash point of 194.2ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 103878-83-7
Jingsj CID: J-1987527-9
Molecular Formula: C₈H₁₁Cl₂N₃O
Chinese Name: 拉扎贝胺盐酸盐
Molecular Weight: 236.09800 g/mol
Category: Organic Acids
Last updated: 8/21/2026

No offers for this compound yet.

Request a quote

Physicochemical Properties

Boiling Point	397.4ºC at 760mmHg
Flash Point	194.2ºC
Exact Mass	235.02800
PSA	68.01000
LogP	2.31670
Vapor Pressure	1.59E-06mmHg at 25°C

Activity & Biological Data

Target	MAO-B:0.4 nM (IC50)
Additional Information	[1]. Saura J, et al. Quantitative enzyme radioautography with 3H-Ro 41-1049 and 3H-Ro 19-6327 in vitro: localization and abundance of MAO-A and MAO-B in rat CNS, peripheral organs, and human brain. J Neurosci. 1992 May;12(5):1977-99. [2]. Bondiolotti GP, et al. In vitro effects on monoamine uptake and release by the reversible monoamine oxidase-B inhibitors lazabemide and N-(2-aminoethyl)-p-chlorobenzamide: a comparison with L-deprenyl. Biochem Pharmacol. 1995 Jun 29;50(1):97-102. [3]. Guimaraes J, et al. The activity of MAO A and B in rat renal cells and tubules. Life Sci. 1998;62(8):727-37. [4]. Suzuki T, et al. MAO inhibitors, clorgyline and lazabemide, prevent hydroxyl radical generation caused by brain ischemia/reperfusion in mice. Pharmacology. 1995 Jun;50(6):357-62.

Target

MAO-B:0.4 nM (IC50)

Additional Information

[1]. Saura J, et al. Quantitative enzyme radioautography with 3H-Ro 41-1049 and 3H-Ro 19-6327 in vitro: localization and abundance of MAO-A and MAO-B in rat CNS, peripheral organs, and human brain. J Neurosci. 1992 May;12(5):1977-99. [2]. Bondiolotti GP, et al. In vitro effects on monoamine uptake and release by the reversible monoamine oxidase-B inhibitors lazabemide and N-(2-aminoethyl)-p-chlorobenzamide: a comparison with L-deprenyl. Biochem Pharmacol. 1995 Jun 29;50(1):97-102. [3]. Guimaraes J, et al. The activity of MAO A and B in rat renal cells and tubules. Life Sci. 1998;62(8):727-37. [4]. Suzuki T, et al. MAO inhibitors, clorgyline and lazabemide, prevent hydroxyl radical generation caused by brain ischemia/reperfusion in mice. Pharmacology. 1995 Jun;50(6):357-62.

Frequently Asked Questions

What is the CAS number of Lazabemide hydrochloride?

The CAS number of Lazabemide hydrochloride is 103878-83-7.

What are the molecular formula and molecular weight of Lazabemide hydrochloride?

Lazabemide hydrochloride has molecular formula C8H11Cl2N3O and molecular weight 236.09800 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Lazabemide hydrochloride (CAS 103878-83-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1987527-9 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.