Devazepide

地伐西匹

Also known as: L-364718, MK-329, (S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide, N-[(3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide, 1H-Indole-2-carboxamide, N-[(3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-

Devazepide (CAS 103420-77-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C25H20N4O2 and a molecular weight of 408.45200 g/mol. It is also known as L-364718, MK-329 and (S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide. Key properties include a boiling point of 758.6ºC at 760mmHg, a density of 1.31g/cm3 and a flash point of 412.6ºC. It is classified under GHS with signal word Danger and hazard statements H300. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
103420-77-5
Jingsj CID
J-1985341-1
Molecular Formula
C25H20N4O2
Chinese Name
地伐西匹
Molecular Weight
408.45200 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point758.6ºC at 760mmHg
Density1.31g/cm3
Flash Point412.6ºC
Exact Mass408.15900
PSA77.56000
LogP3.62930
Vapor Pressure6.56E-23mmHg at 25°C
Refractive Index1.696

GHS Safety & Compliance

Acute ToxicitySignal word: Danger
  • H300

Activity & Biological Data

TargetIC50: 45 pM (Rat pancreatic CCK receptor), 81 pM (Bovine gallbladder CCK receptor), 245 nM (Guinea pig brain CCK receptor)[1]
Additional Information[1]. Chang RS, et al. Biochemical and pharmacological characterization of an extremely potent and selective nonpeptide cholecystokinin antagonist. Proc Natl Acad Sci U S A. 1986 Jul;83(13):4923-6.

Frequently Asked Questions

What is the CAS number of Devazepide?

The CAS number of Devazepide is 103420-77-5.

What are the molecular formula and molecular weight of Devazepide?

Devazepide has molecular formula C25H20N4O2 and molecular weight 408.45200 g/mol.

Is Devazepide hazardous?

Devazepide has GHS signal word Danger and hazard statements H300.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Devazepide (CAS 103420-77-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1985341-1 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.