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Fraxetin

Also known as: 7,8-dihydroxy-6-methoxycoumarin, 7,8-dihydroxy-6-methoxy-2H-chromen-2-one, 7,8-dihydroxy-6-methoxy-2-benzopyrone, 7,8-dihydroxy-6-methoxy-2H-1-benzopyran-2-one, 6-methoxy-7,8-dihydroxycoumarin, Coumarin, 7,8-dihydroxy-6-methoxy-, Fratexin, Fraxetol

Fraxetin (CAS 574-84-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C10H8O5 and a molecular weight of 208.167 g/mol. Key properties include a melting point of 230-232°C, a boiling point of 472.0±45.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 196.0±22.2 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H312 — Harmful in contact with skin and H332 — Harmful if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
574-84-5
Jingsj CID
J-9891-9
Molecular Formula
C10H8O5
Molecular Weight
208.167 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point230-232°C
Boiling Point472.0±45.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point196.0±22.2 °C
Exact Mass208.037170
PSA79.90000
LogP0.59
Vapor Pressure0.0±1.2 mmHg at 25°C
Refractive Index1.648

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed
  • H312 — Harmful in contact with skin
  • H332 — Harmful if inhaled
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Chen X, et al. The therapeutic effect of fraxetin on ethanol-induced hepatic fibrosis by enhancing ethanol metabolism, inhibiting oxidative stress and modulating inflammatory mediators in rats. Int Immunopharmacol. 2018 Mar;56:98-104. [2]. Liu G, et al. Effect of fraxetin on proliferation and apoptosis in breast cancer cells. Oncol Lett. 2017 Dec;14(6):7374-7378.

Customs & Trade Information

HS Code2932209090
Summary2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Fraxetin?

The CAS number of Fraxetin is 574-84-5.

What are the molecular formula and molecular weight of Fraxetin?

Fraxetin has molecular formula C10H8O5 and molecular weight 208.167 g/mol.

Is Fraxetin hazardous?

Fraxetin has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H312 — Harmful in contact with skin; H332 — Harmful if inhaled.

What are the upstream and downstream products of Fraxetin?

For Fraxetin, Upstream Products: 2,3-dihydroxy-4-methoxybenzaldehyde, 2,3,4-Trimethoxybenzaldehyde, 8-Acetyl-7-methoxycoumarin; Downstream Products: Isofraxidin, Fraxidin, 7,8-Methylenedioxy-6-methoxycoumarin.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Fraxetin (CAS 574-84-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-9891-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.