Genistein

Also known as: 4',5,7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 5,7,4'-Trihydroxyisoflavone, Genisteol, Prunetol, Sophoricol, Bonistein, GeniVida

Genistein (CAS 446-72-0) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C15H10O5 and a molecular weight of 270.237 g/mol. Key properties include a melting point of 297-298 °C, a boiling point of 555.5±50.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 217.1±23.6 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 446-72-0
Jingsj CID: J-977206-9
Molecular Formula: C₁₅H₁₀O₅
Molecular Weight: 270.237 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	297-298 °C
Boiling Point	555.5±50.0 °C at 760 mmHg
Density	1.5±0.1 g/cm3
Flash Point	217.1±23.6 °C
Exact Mass	270.052826
PSA	90.90000
LogP	2.96
Vapor Pressure	0.0±1.6 mmHg at 25°C
Refractive Index	1.732
Additional Property	insoluble

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed

Activity & Biological Data

Target	EGFR:0.6 μM (IC50, Cell Assay)
Additional Information	[1]. Peterson G, et al. Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells. Cell Growth Differ. 1996 Oct;7(10):1345-51. [2]. Jalili C, et al. Effect of Genistein on reproductive parameter and serum nitric oxide levels in morphine-treated mice. Int J Reprod Biomed (Yazd). 2016 Feb;14(2):95-102. [3]. Ding S, et al. Environmentally Relevant Dose of Bisphenol A Does Not Affect Lipid Metabolism and Has No Synergetic or Antagonistic Effects on Genistein's Beneficial Roles on Lipid Metabolism. PLoS One. 2016 May 12;11(5):e0155352.

Target

EGFR:0.6 μM (IC50, Cell Assay)

Additional Information

[1]. Peterson G, et al. Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells. Cell Growth Differ. 1996 Oct;7(10):1345-51. [2]. Jalili C, et al. Effect of Genistein on reproductive parameter and serum nitric oxide levels in morphine-treated mice. Int J Reprod Biomed (Yazd). 2016 Feb;14(2):95-102. [3]. Ding S, et al. Environmentally Relevant Dose of Bisphenol A Does Not Affect Lipid Metabolism and Has No Synergetic or Antagonistic Effects on Genistein's Beneficial Roles on Lipid Metabolism. PLoS One. 2016 May 12;11(5):e0155352.

Customs & Trade Information

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Genistein?

The CAS number of Genistein is 446-72-0.

What are the molecular formula and molecular weight of Genistein?

Genistein has molecular formula C15H10O5 and molecular weight 270.237 g/mol.

Is Genistein hazardous?

Genistein has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of Genistein?

For Genistein, Upstream Products: Sodium formate, Propionyl chloride, Formic Acid; Downstream Products: 5-Hydroxy-4',7-dimethoxyisoflavone, Prunetin, Phloroglucinol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Genistein (CAS 446-72-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-977206-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.