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1-Acetyl-4-(4-hydroxyphenyl)piperazine

Also known as: 4-(1-Acetylpiperazin-4-yl)phenol, 4-(4-Acetylpiperazino)phenol, 1-[4-(4-Hydroxyphenyl)-1-piperazinyl]ethanone, 1-[4-(4-Hydroxyphenyl)piperazin-1-yl]ethanone, N-Acetyl-4-(4-hydroxyphenyl)piperazine, N-Acetyl-4-hydroxyphenyl piperazine, 1-[4-(4-Hydroxyphenyl)piperazin-1-yl]ethan-1-one, Ethanone, 1-[4-(4-hydroxyphenyl)-1-piperazinyl]-, Piperazine, 1-acetyl-4-(4-hydroxyphenyl)-, MFCD00044905, TIMTEC-BB SBB003353

1-Acetyl-4-(4-hydroxyphenyl)piperazine (CAS 67914-60-7) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C12H16N2O2 and a molecular weight of 220.268 g/mol. Key properties include a melting point of 180-185 °C(lit.), a boiling point of 456.5±40.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 229.9±27.3 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
67914-60-7
Jingsj CID
J-932220-7
Molecular Formula
C12H16N2O2
Molecular Weight
220.268 g/mol
Category
Aromatic Hydrocarbons
Last updated
8/21/2026

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Physicochemical Properties

Melting Point180-185 °C(lit.)
Boiling Point456.5±40.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point229.9±27.3 °C
Exact Mass220.121185
PSA43.78000
LogP0.19
Vapor Pressure0.0±1.2 mmHg at 25°C
Refractive Index1.585
Additional Property4.3 g/L (20 ºC)

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2933599090
Summary2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 1-Acetyl-4-(4-hydroxyphenyl)piperazine?

The CAS number of 1-Acetyl-4-(4-hydroxyphenyl)piperazine is 67914-60-7.

What are the molecular formula and molecular weight of 1-Acetyl-4-(4-hydroxyphenyl)piperazine?

1-Acetyl-4-(4-hydroxyphenyl)piperazine has molecular formula C12H16N2O2 and molecular weight 220.268 g/mol.

Is 1-Acetyl-4-(4-hydroxyphenyl)piperazine hazardous?

1-Acetyl-4-(4-hydroxyphenyl)piperazine has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 1-Acetyl-4-(4-hydroxyphenyl)piperazine?

For 1-Acetyl-4-(4-hydroxyphenyl)piperazine, Upstream Products: 1-(4-Hydroxyphenyl)piperazine, Aqueous ammonia, Diethyl azodicarboxylate; Downstream Products: Ketoconazole.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "1-Acetyl-4-(4-hydroxyphenyl)piperazine (CAS 67914-60-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-932220-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.