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1-(4-Hydroxyphenyl)piperazine

Also known as: 4-(1-Piperazino)phenol, 4-(piperazin-1-yl)phenol, N-(4-Hydroxyphenyl)piperazine, 4-Piperazin-1-ylphenol, 4-Piperazinylphenol, 4-(1-Piperazinyl)phenol

1-(4-Hydroxyphenyl)piperazine (CAS 56621-48-8) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C10H14N2O and a molecular weight of 178.231 g/mol. Key properties include a melting point of 220 °C, a boiling point of 371.3±27.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 178.3±23.7 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
56621-48-8
Jingsj CID
J-49537-4
Molecular Formula
C10H14N2O
Molecular Weight
178.231 g/mol
Category
Aromatic Hydrocarbons
Last updated
8/21/2026

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Physicochemical Properties

Melting Point220 °C
Boiling Point371.3±27.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point178.3±23.7 °C
Exact Mass178.110611
PSA35.50000
LogP0.37
Vapor Pressure0.0±0.9 mmHg at 25°C
Refractive Index1.576

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2933599090
Summary2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 1-(4-Hydroxyphenyl)piperazine?

The CAS number of 1-(4-Hydroxyphenyl)piperazine is 56621-48-8.

What are the molecular formula and molecular weight of 1-(4-Hydroxyphenyl)piperazine?

1-(4-Hydroxyphenyl)piperazine has molecular formula C10H14N2O and molecular weight 178.231 g/mol.

Is 1-(4-Hydroxyphenyl)piperazine hazardous?

1-(4-Hydroxyphenyl)piperazine has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 1-(4-Hydroxyphenyl)piperazine?

For 1-(4-Hydroxyphenyl)piperazine, Upstream Products: 1-(4-Methoxyphenyl)piperazine, Piperazine, 4-Bromophenol; Downstream Products: 1-isopropyl-4-(4-hydroxyphenyl)piperazine, 1-Acetyl-4-(4-hydroxyphenyl)piperazine, Ketoconazole.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "1-(4-Hydroxyphenyl)piperazine (CAS 56621-48-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-49537-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.