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Phenylbutazone

Also known as: Butazolidin, 4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione, 1,2-Diphenyl-4-butyl-3,5-pyrazolidinedione, Diphenylbutazone, Phenylbutazone (USAN), Azolid, Butadione, Butalidon, Butapirazol, Butazina, Butidiona, Fenibutazona, Fenilbutina, Fenotone, Fenylbutazon, Mephabutazon, Phen-Buta, Reudo, Reumazin, Robizone

Phenylbutazone (CAS 50-33-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C19H20N2O2 and a molecular weight of 308.38100 g/mol. Key properties include a melting point of 104-107 °C, a boiling point of 240.4±23.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 99.2±22.6 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H312 — Harmful in contact with skin and H332 — Harmful if inhaled. No supplier offers are currently listed; request a quote. Record last updated Nov 2, 2026.

CAS No.
50-33-9
Jingsj CID
J-8255-3
Molecular Formula
C19H20N2O2
Molecular Weight
308.38100 g/mol
Category
Organic Compounds
Last updated
11/2/2026

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Physicochemical Properties

Melting Point104-107 °C
Boiling Point240.4±23.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point99.2±22.6 °C
Exact Mass184.984009
PSA40.62000
LogP2.76
Vapor Pressure0.0±0.5 mmHg at 25°C
Refractive Index1.613
StabilityStable. Incompatible with strong oxidizing agents, strong acids, strong bases.
Additional Property<0.1 g/100 mL at 23.5 ºC

GHS Safety & Compliance

Acute ToxicitySignal word: Danger
  • H301 — Toxic if swallowed
  • H312 — Harmful in contact with skin
  • H332 — Harmful if inhaled
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

TargetCOX-2:1.1 μM (IC50) COX-1:3.7 μM (IC50)
Additional Information[1]. Beretta C, et al. COX-1 and COX-2 inhibition in horse blood by phenylbutazone, flunixin, carprofen and meloxicam: an in vitro analysis. Pharmacol Res. 2005 Oct;52(4):302-6.

Customs & Trade Information

HS Code2933199090
Summary2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Phenylbutazone?

The CAS number of Phenylbutazone is 50-33-9.

What are the molecular formula and molecular weight of Phenylbutazone?

Phenylbutazone has molecular formula C19H20N2O2 and molecular weight 308.38100 g/mol.

Is Phenylbutazone hazardous?

Phenylbutazone has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H312 — Harmful in contact with skin; H332 — Harmful if inhaled.

What are the upstream and downstream products of Phenylbutazone?

For Phenylbutazone, Upstream Products: Diethyl 2-butylmalonate, 1,2-Diphenylhydrazine, 1-Bromobutane; Downstream Products: Bumadizone, Oxyphenbutazone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Phenylbutazone (CAS 50-33-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-8255-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.