Hispidulin
Also known as: 4',5,7-Trihydroxy-6-methoxyflavone, Scutellarein 6-methyl ether, 6-Methoxyapigenin, 6-Methylscutellarein, Dinatin, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxychromen-4-one, 6-O-Methoxyapigenin, 6-O-Methylapigenin, TCMDC-123942
Hispidulin (CAS 1447-88-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H12O6 and a molecular weight of 300.263 g/mol. Key properties include a boiling point of 601.5±55.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 230.1±25.0 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. It is listed by 1 supplier; request a quote for pricing. Record last updated Aug 21, 2026.
- CAS No.
- 1447-88-7
- Jingsj CID
- J-30957-9
- Molecular Formula
- C16H12O6
- Molecular Weight
- 300.263 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
| Supplier | Purity / Pack | Base Price | Unit Price | Origin | |
|---|---|---|---|---|---|
Made to Order | - | - | CN China |
Physicochemical Properties
| Boiling Point | 601.5±55.0 °C at 760 mmHg |
|---|---|
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 230.1±25.0 °C |
| Exact Mass | 300.063385 |
| PSA | 100.13000 |
| LogP | 1.60 |
| Appearance | white to beige |
| Vapor Pressure | 0.0±1.8 mmHg at 25°C |
| Refractive Index | 1.697 |
| Storage Conditions | Desiccate at -20°C |
| Additional Property | DMSO: soluble20mg/mL, clear |
GHS Safety & Compliance
- H302 — Harmful if swallowed
Activity & Biological Data
| Target | IC50: 2.71 μM (Pim-1)[1] |
|---|---|
| Additional Information | [1]. Chao SW, et al. Total Synthesis of Hispidulin and the Structural Basis for Its Inhibition of Proto-oncogene KinasePim-1. J Nat Prod. 2015 Aug 28;78(8):1969-76. [2]. Gao H, et al. Hispidulin induces apoptosis through mitochondrial dysfunction and inhibition of P13k/Akt signalling pathway in HepG2 cancer cells. Cell Biochem Biophys. 2014 May;69(1):27-34. [3]. Zhou R, et al. Hispidulin exerts anti-osteoporotic activity in ovariectomized mice via activating AMPK signaling pathway. Cell Biochem Biophys. 2014 Jun;69(2):311-7. [4]. Lin TY, et al. Protective effect of hispidulin on kainic acid-induced seizures and neurotoxicity in rats. Eur J Pharmacol. 2015 May 15;755:6-15. |
Customs & Trade Information
| HS Code | 2914509090 |
|---|---|
| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Hispidulin?
The CAS number of Hispidulin is 1447-88-7.
What are the molecular formula and molecular weight of Hispidulin?
Hispidulin has molecular formula C16H12O6 and molecular weight 300.263 g/mol.
Which suppliers offer Hispidulin?
1 supplier(s) listed; request a quote for pricing.
Is Hispidulin hazardous?
Hispidulin has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.
What are the upstream and downstream products of Hispidulin?
For Hispidulin, Upstream Products: 2'-Hydroxy-4',6'-dimethoxyacetophenone, 4-(benzyloxy)benzoyl chloride, 2,4,6-Trihydroxyacetophenone; Downstream Products: Scutellarein.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Hispidulin (CAS 1447-88-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-30957-9 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.