Aprepitant

阿瑞匹坦

Also known as: MK-0869, MK-869, L-754030, Emend, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one, 5-{[(2R,3S)-2-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)-4-morpholinyl]methyl}-1,2-dihydro-3H-1,2,4-triazol-3-one, [3H]-Aprepitant, Aprepitant (MK-0869, L-754030), Fosaprepitant Impurity 8

CAS No.
170729-80-3
Jingsj CID
J-5957-6
Molecular Formula
C23H21F7N4O3
Chinese Name
阿瑞匹坦
Molecular Weight
534.427 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point75-76 °C(lit.)
Density1.5±0.1 g/cm3

GHS Safety & Compliance

IrritantSignal word: Warning

Frequently Asked Questions

What is the CAS number of Aprepitant?

170729-80-3

What are the molecular formula and molecular weight of Aprepitant?

C23H21F7N4O3, molecular weight 534.427 g/mol

Is Aprepitant hazardous?

Warning

Data compiled from public chemical databases and supplier catalogs; verify specifications with suppliers before purchase. · Last updated: 8/21/2026