Kaempferide

Also known as: 3,5,7-Trihydroxy-4'-methoxyflavone, 4'-Methoxy-3,5,7-trihydroxyflavone, 3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one, 4'-Methylkaempferol, 4'-O-Methylkaempferol, Kaempferid, Kaempferol 4'-methyl ether

Kaempferide (CAS 491-54-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H12O6 and a molecular weight of 300.263 g/mol. Key properties include a melting point of 156-157ºC(lit.), a boiling point of 543.8±50.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 207.1±23.6 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 491-54-3
Jingsj CID: J-49282-0
Molecular Formula: C₁₆H₁₂O₆
Molecular Weight: 300.263 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	156-157ºC(lit.)
Boiling Point	543.8±50.0 °C at 760 mmHg
Density	1.5±0.1 g/cm3
Flash Point	207.1±23.6 °C
Exact Mass	300.063385
PSA	100.13000
LogP	2.74
Vapor Pressure	0.0±1.5 mmHg at 25°C
Refractive Index	1.710
Storage Conditions	2-8°C

Activity & Biological Data

Additional Information	[1]. Otake Y, Walle T. Oxidation of the flavonoids galangin and kaempferide by human liver microsomes and CYP1A1, CYP1A2, and CYP2C9. Drug Metab Dispos. 2002 Feb;30(2):103-5. [2]. Martineti V, Tognarini I, Azzari C et al. Inhibition of in vitro growth and arrest in the G0/G1 phase of HCT8 line human colon cancer cells by kaempferide triglycoside from Dianthus caryophyllus. Phytother Res. 2010 Sep;24(9):1302-8. [3]. Pahua-Ramos, Maria Elena; Ortiz-Moreno, Alicia; Chamorro-Cevallos, German et al. Hypolipidemic Effect of Avocado (Persea americana Mill) Seed in a Hypercholesterolemic Mouse Model. Plant Foods for Human Nutrition (New York, NY, United States) (2012), 67(1), 10-16. [4]. Soucek, Pavel; Kondrova, Eliska; Hermanek, Josef et al. New model system for testing effects of flavonoids on doxorubicin-related formation of hydroxyl radicals. Anti-Cancer Drugs (2011), 22(2), 176-184.

Additional Information

[1]. Otake Y, Walle T. Oxidation of the flavonoids galangin and kaempferide by human liver microsomes and CYP1A1, CYP1A2, and CYP2C9. Drug Metab Dispos. 2002 Feb;30(2):103-5. [2]. Martineti V, Tognarini I, Azzari C et al. Inhibition of in vitro growth and arrest in the G0/G1 phase of HCT8 line human colon cancer cells by kaempferide triglycoside from Dianthus caryophyllus. Phytother Res. 2010 Sep;24(9):1302-8. [3]. Pahua-Ramos, Maria Elena; Ortiz-Moreno, Alicia; Chamorro-Cevallos, German et al. Hypolipidemic Effect of Avocado (Persea americana Mill) Seed in a Hypercholesterolemic Mouse Model. Plant Foods for Human Nutrition (New York, NY, United States) (2012), 67(1), 10-16. [4]. Soucek, Pavel; Kondrova, Eliska; Hermanek, Josef et al. New model system for testing effects of flavonoids on doxorubicin-related formation of hydroxyl radicals. Anti-Cancer Drugs (2011), 22(2), 176-184.

Frequently Asked Questions

What is the CAS number of Kaempferide?

The CAS number of Kaempferide is 491-54-3.

What are the molecular formula and molecular weight of Kaempferide?

Kaempferide has molecular formula C16H12O6 and molecular weight 300.263 g/mol.

What are the upstream and downstream products of Kaempferide?

For Kaempferide, Upstream Products: 4-Methoxybenzaldehyde, 4-Methoxybenzoic anhydride, Kaempferol; Downstream Products: 4-Methoxybenzoic acid, Oxalic acid, Formic Acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Kaempferide (CAS 491-54-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-49282-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.