Vanillic acid
Also known as: 4-Hydroxy-3-methoxybenzoic acid, 3-Methoxy-4-hydroxybenzoic acid, Protocatechuic acid 3-methyl ether, FEMA 3988
Vanillic acid (CAS 121-34-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C8H8O4 and a molecular weight of 168.147 g/mol. Key properties include a melting point of 208-210 °C(lit.), a boiling point of 353.4±27.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 149.4±17.2 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 121-34-6
- Jingsj CID
- J-48022-8
- Molecular Formula
- C8H8O4
- Molecular Weight
- 168.147 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 208-210 °C(lit.) |
|---|---|
| Boiling Point | 353.4±27.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 149.4±17.2 °C |
| Exact Mass | 168.042252 |
| PSA | 66.76000 |
| LogP | 1.33 |
| Vapor Pressure | 0.0±0.8 mmHg at 25°C |
| Refractive Index | 1.586 |
Activity & Biological Data
| Target | p65 |
|---|---|
| Additional Information | [1]. Calixto-Campos C, et al. Vanillic acid Inhibits Inflammatory Pain by Inhibiting Neutrophil Recruitment, Oxidative Stress, Cytokine Production, and NFκB Activation in Mice. J Nat Prod. 2015 Aug 28;78(8):1799-808. [2]. Amin FU, et al. Vanillic acid attenuates Aβ 1-42 -induced oxidative stress and cognitive impairment in mice. Sci Rep. 2017 Jan 18;7:40753. |
Customs & Trade Information
| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Vanillic acid?
The CAS number of Vanillic acid is 121-34-6.
What are the molecular formula and molecular weight of Vanillic acid?
Vanillic acid has molecular formula C8H8O4 and molecular weight 168.147 g/mol.
What are the upstream and downstream products of Vanillic acid?
For Vanillic acid, Upstream Products: Vanillin, 4-(Benzyloxy)-3-methoxybenzaldehyde, 2-Methoxy-4-methylphenol; Downstream Products: 3-O-Methylgallic acid, 2-Methoxy-4-nitrophenol, 4-Hydroxy-3-methoxy-5-nitrobenzoic acid.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Vanillic acid (CAS 121-34-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-48022-8 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.