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4-Hydroxy-3-methoxybenzonitrile

Also known as: Vanillonitrile, Vanilonitrile, 4-Cyano-2-methoxyphenol, 3-Methoxy-4-hydroxybenzonitrile, AKOS B004154, Benzonitrile, 4-hydroxy-3-methoxy-

4-Hydroxy-3-methoxybenzonitrile (CAS 4421-08-3) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C8H7NO2 and a molecular weight of 149.147 g/mol. Key properties include a melting point of 85-87 °C(lit.), a boiling point of 291.6±30.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 130.1±24.6 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H312 — Harmful in contact with skin and H332 — Harmful if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
4421-08-3
Jingsj CID
J-26009-3
Molecular Formula
C8H7NO2
Molecular Weight
149.147 g/mol
Category
Aromatic Hydrocarbons
Last updated
8/21/2026

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Physicochemical Properties

Melting Point85-87 °C(lit.)
Boiling Point291.6±30.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point130.1±24.6 °C
Exact Mass149.047684
PSA53.25000
LogP1.18
Vapor Pressure0.0±0.6 mmHg at 25°C
Refractive Index1.569

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed
  • H312 — Harmful in contact with skin
  • H332 — Harmful if inhaled
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2926909090
SummaryHS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 4-Hydroxy-3-methoxybenzonitrile?

The CAS number of 4-Hydroxy-3-methoxybenzonitrile is 4421-08-3.

What are the molecular formula and molecular weight of 4-Hydroxy-3-methoxybenzonitrile?

4-Hydroxy-3-methoxybenzonitrile has molecular formula C8H7NO2 and molecular weight 149.147 g/mol.

Is 4-Hydroxy-3-methoxybenzonitrile hazardous?

4-Hydroxy-3-methoxybenzonitrile has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H312 — Harmful in contact with skin; H332 — Harmful if inhaled.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "4-Hydroxy-3-methoxybenzonitrile (CAS 4421-08-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-26009-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.