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Sumatriptan

Also known as: 1H-Indole-5-methanesulfonamide, 3-[2-(dimethylamino)ethyl]-N-methyl-, 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide, GR 43175C, GR 43175, IMITREX, IMIGRAN, Sumatriptan base, MFCD00902856

Sumatriptan (CAS 103628-46-2) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C14H21N3O2S and a molecular weight of 295.400 g/mol. Key properties include a melting point of 169-171°C, a boiling point of 497.7±55.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 254.8±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
103628-46-2
Jingsj CID
J-47551-4
Molecular Formula
C14H21N3O2S
Molecular Weight
295.400 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point169-171°C
Boiling Point497.7±55.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point254.8±31.5 °C
Exact Mass295.135437
PSA73.58000
LogP0.67
Vapor Pressure0.0±1.3 mmHg at 25°C
Refractive Index1.610
Storage Conditions2-8°C
Additional Property21.4 mg/mL

Activity & Biological Data

Target5-HT1A Receptor:100 nM (Ki) 5-HT1B Receptor:27 nM (Ki) 5-HT1D Receptor:17 nM (Ki)
Additional Information[1]. S J Peroutka, et al. Sumatriptan (GR 43175) interacts selectively with 5-HT1B and 5-HT1D binding sites. Eur J Pharmacol. 1989 Apr 12;163(1):133-6. [2]. K L Dechant, et al. Sumatriptan. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the acute treatment of migraine and cluster headache. Drugs. 1992 May;43(5):776-98.

Customs & Trade Information

HS Code29280090

Frequently Asked Questions

What is the CAS number of Sumatriptan?

The CAS number of Sumatriptan is 103628-46-2.

What are the molecular formula and molecular weight of Sumatriptan?

Sumatriptan has molecular formula C14H21N3O2S and molecular weight 295.400 g/mol.

What are the upstream and downstream products of Sumatriptan?

For Sumatriptan, Upstream Products: 4,4-dimethoxy-N,N-dimethylbutan-1-amine, 4-Hydrazino-N-methylbenzenemethanesulfonamide, tryptamine; Downstream Products: Sumatriptan N-Oxide, Sumatriptan succinate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Sumatriptan (CAS 103628-46-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-47551-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.