Ibuprofen sodium

Also known as: Ibuprofen sodium salt, Sodium 2-(4-isobutylphenyl)propionate, Sodium ibuprofen, α-Methyl-4-(2-methylpropyl)benzeneacetic acid sodium salt, p-Isobutylhydratropic acid sodium salt, 2-(p-Isobutylphenyl)propionic acid sodium salt, (±)-Ibuprofen sodium, sodium 2-[4-(2-methylpropyl)phenyl]propanoate

Ibuprofen sodium (CAS 31121-93-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C13H17NaO2 and a molecular weight of 228.26300 g/mol. Key properties include a melting point of 75-77ºC, a boiling point of 319.6ºC at 760 mmHg, a density of 1.029g/cm3 and a flash point of 216.7ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 31121-93-4
Jingsj CID: J-4558-9
Molecular Formula: C₁₃H₁₇NaO₂
Molecular Weight: 228.26300 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	75-77ºC
Boiling Point	319.6ºC at 760 mmHg
Density	1.029g/cm3
Flash Point	216.7ºC
Exact Mass	228.11300
PSA	40.13000
LogP	1.73850
Storage Conditions	2-8°C
Stability	Stable. Incompatible with strong oxidizing agents
Additional Property	H2O: 100 mg/mL, may be clear to slightly hazy

Activity & Biological Data

Target	COX-1:13 μM (IC50) COX-2:370 μM (IC50)
Additional Information	[1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7. [2]. Hassan Akrami, et al. Inhibitory effect of ibuprofen on tumor survival and angiogenesis in gastric cancer cell. Tumour Biol. 2015 May;36(5):3237-43. [3]. Sharon M Rymut, et al. Ibuprofen regulation of microtubule dynamics in cystic fibrosis epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L317-27. [4]. Emmanuelle Bignon, et al. Ibuprofen and ketoprofen potentiate UVA-induced cell death by a photosensitization process. Sci Rep. 2017 Aug 21;7(1):8885. [5]. Nathan D Pennock, et al. Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer. J Immunother Cancer. 2018 Oct 1;6(1):98. [6]. Thomas Krøigård, et al. Protective effect of ibuprofen in a rat model of chronic oxaliplatin-induced peripheral neuropathy. Exp Brain Res. 2019 Oct;237(10):2645-2651. [7]. Sarah Ilkhanipour Rooney, et al. Ibuprofen Differentially Affects Supraspinatus Muscle and Tendon Adaptations to Exercise in a Rat Model. Am J Sports Med. 2016 Sep;44(9):2237-45. [8]. M W Konstan, et al. Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection. Implications for antiinflammatory therapy in cystic fibrosis. Am Rev Respir Dis. 1990 Jan;141(1):186-92.

Target

COX-1:13 μM (IC50) COX-2:370 μM (IC50)

Additional Information

[1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7. [2]. Hassan Akrami, et al. Inhibitory effect of ibuprofen on tumor survival and angiogenesis in gastric cancer cell. Tumour Biol. 2015 May;36(5):3237-43. [3]. Sharon M Rymut, et al. Ibuprofen regulation of microtubule dynamics in cystic fibrosis epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L317-27. [4]. Emmanuelle Bignon, et al. Ibuprofen and ketoprofen potentiate UVA-induced cell death by a photosensitization process. Sci Rep. 2017 Aug 21;7(1):8885. [5]. Nathan D Pennock, et al. Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer. J Immunother Cancer. 2018 Oct 1;6(1):98. [6]. Thomas Krøigård, et al. Protective effect of ibuprofen in a rat model of chronic oxaliplatin-induced peripheral neuropathy. Exp Brain Res. 2019 Oct;237(10):2645-2651. [7]. Sarah Ilkhanipour Rooney, et al. Ibuprofen Differentially Affects Supraspinatus Muscle and Tendon Adaptations to Exercise in a Rat Model. Am J Sports Med. 2016 Sep;44(9):2237-45. [8]. M W Konstan, et al. Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection. Implications for antiinflammatory therapy in cystic fibrosis. Am Rev Respir Dis. 1990 Jan;141(1):186-92.

Customs & Trade Information

HS Code	2916399090
Summary	2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Ibuprofen sodium?

The CAS number of Ibuprofen sodium is 31121-93-4.

What are the molecular formula and molecular weight of Ibuprofen sodium?

Ibuprofen sodium has molecular formula C13H17NaO2 and molecular weight 228.26300 g/mol.

What are the upstream and downstream products of Ibuprofen sodium?

For Ibuprofen sodium, Upstream Products: Ibuprofen, (S)-(+)-Ibuprofen; Downstream Products: 2-(4-isobutylphenyl)propan-1-ol, (S)-(+)-Ibuprofen.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Ibuprofen sodium (CAS 31121-93-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-4558-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.