Ibuprofen
Also known as: Advil, Motrin, Brufen, Nurofen, Dolgit, Rufen, Fenbid, 2-(4-Isobutylphenyl)propionic acid, 2-(4-Isobutylphenyl)propanoic acid, α-Methyl-4-(2-methylpropyl)benzeneacetic acid, 4-Isobutyl-α-methylphenylacetic acid, (±)-Ibuprofen, (RS)-Ibuprofen, p-Isobutylhydratropic acid, UNII:WK2XYI10QM, MFCD00010393
Ibuprofen (CAS 15687-27-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C13H18O2 and a molecular weight of 206.281 g/mol. Key properties include a melting point of 77-78 °C(lit.), a boiling point of 319.6±11.0 °C at 760 mmHg, a density of 1.0±0.1 g/cm3 and a flash point of 216.7±14.4 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 15687-27-1
- Jingsj CID
- J-33623-2
- Molecular Formula
- C13H18O2
- Molecular Weight
- 206.281 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 77-78 °C(lit.) |
|---|---|
| Boiling Point | 319.6±11.0 °C at 760 mmHg |
| Density | 1.0±0.1 g/cm3 |
| Flash Point | 216.7±14.4 °C |
| Exact Mass | 206.130676 |
| PSA | 37.30000 |
| LogP | 3.72 |
| Vapor Pressure | 0.0±0.7 mmHg at 25°C |
| Refractive Index | 1.519 |
| Additional Property | insoluble |
GHS Safety & Compliance
- H302 — Harmful if swallowed
Activity & Biological Data
| Target | COX-1:13 μM (IC50) COX-2:370 μM (IC50) |
|---|---|
| Additional Information | [1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7. [2]. Palayoor ST, et al. Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen. Oncogene. 1999 Dec 2;18(51):7389-94. [3]. Khwaja F, et al. Ibuprofen inhibits survival of bladder cancer cells by induced expression of the p75NTR tumor suppressor protein. Cancer Res. 2004 Sep 1;64(17):6207-13. [4]. Rao GH, et al. Ibuprofen protects platelet cyclooxygenase from irreversible inhibition by aspirin. Arteriosclerosis. 1983 Jul-Aug;3(4):383-8. [5]. Driban JB, et al. Joint inflammation and early degeneration induced by high-force reaching are attenuated by ibuprofen in an animal model of work-related musculoskeletal disorder. J Biomed Biotechnol. 2011;2011:691412 |
Customs & Trade Information
| HS Code | 2916392000 |
|---|---|
| Summary | 2916392000 2-(4-isobutylphenyl)propanoic acid。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:6.5%。General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Ibuprofen?
The CAS number of Ibuprofen is 15687-27-1.
What are the molecular formula and molecular weight of Ibuprofen?
Ibuprofen has molecular formula C13H18O2 and molecular weight 206.281 g/mol.
Is Ibuprofen hazardous?
Ibuprofen has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.
What are the upstream and downstream products of Ibuprofen?
For Ibuprofen, Upstream Products: Ethyl 2-(4-isobutylphenyl)propanoate, p-Isobutylstyrene, 1-(4-Isobutylphenyl)ethanol; Downstream Products: Ibuprofen sodium, Ethyl 2-(4-isobutylphenyl)propanoate, 4-Isobutylbenzaldehyde.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Ibuprofen (CAS 15687-27-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-33623-2 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.