Rosiglitazone maleate

Also known as: BRL 49653, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione maleate salt, Rosiglitazone maleate salt

Rosiglitazone maleate (CAS 155141-29-0) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C22H23N3O7S and a molecular weight of 473.50 g/mol. Key properties include a melting point of 235-240°C, a boiling point of 585ºC at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 307.6ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 155141-29-0
Jingsj CID: J-44341-4
Molecular Formula: C₂₂H₂₃N₃O₇S
Molecular Weight: 473.50 g/mol
Category: Organic Acids
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	235-240°C
Boiling Point	585ºC at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	307.6ºC
PSA	96.83000
LogP	2.38
Refractive Index	1.688

Activity & Biological Data

Target	PPARγ1:30 nM (EC50) PPARγ2:100 nM (EC50)
Additional Information	[1]. Lehmann JM, et al. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem. 1995 Jun 2;270(22):12953-6. [2]. Willson TM, et al. The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J Med Chem. 1996 Feb 2;39(3):665-8. [3]. Thouennon E, et al. Rosiglitazone-activated PPARγ induces neurotrophic factor-α1 transcription contributing to neuroprotection. J Neurochem. 2015 Aug;134(3):463-70. [4]. Majeed Y, et al. Rapid and contrasting effects of rosiglitazone on transient receptor potential TRPM3 and TRPC5 channels. Mol Pharmacol. 2011 Jun;79(6):1023-30. [5]. Ateyya H, et al. Beneficial effects of rosiglitazone and losartan combination in diabetic rats. Can J Physiol Pharmacol. 2018 Mar;96(3):215-220.

Target

PPARγ1:30 nM (EC50) PPARγ2:100 nM (EC50)

Additional Information

[1]. Lehmann JM, et al. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem. 1995 Jun 2;270(22):12953-6. [2]. Willson TM, et al. The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J Med Chem. 1996 Feb 2;39(3):665-8. [3]. Thouennon E, et al. Rosiglitazone-activated PPARγ induces neurotrophic factor-α1 transcription contributing to neuroprotection. J Neurochem. 2015 Aug;134(3):463-70. [4]. Majeed Y, et al. Rapid and contrasting effects of rosiglitazone on transient receptor potential TRPM3 and TRPC5 channels. Mol Pharmacol. 2011 Jun;79(6):1023-30. [5]. Ateyya H, et al. Beneficial effects of rosiglitazone and losartan combination in diabetic rats. Can J Physiol Pharmacol. 2018 Mar;96(3):215-220.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Rosiglitazone maleate?

The CAS number of Rosiglitazone maleate is 155141-29-0.

What are the molecular formula and molecular weight of Rosiglitazone maleate?

Rosiglitazone maleate has molecular formula C22H23N3O7S and molecular weight 473.50 g/mol.

What are the upstream and downstream products of Rosiglitazone maleate?

For Rosiglitazone maleate, Upstream Products: Maleic acid, Rosiglitazone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Rosiglitazone maleate (CAS 155141-29-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-44341-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.