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Monoethyl fumarate

Also known as: Fumaric acid monoethyl ester, Ethyl hydrogen fumarate, Ethyl fumarate, Monoethyl trans-2-Butenedioate, 2-Butenedioic acid (E)-, monoethyl ester

Monoethyl fumarate (CAS 2459-05-4) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C6H8O4 and a molecular weight of 144.125 g/mol. Key properties include a melting point of 64-69 ºC, a boiling point of 147 ºC (16 mmHg), a density of 1.2±0.1 g/cm3 and a flash point of 109.6±16.1 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
2459-05-4
Jingsj CID
J-44332-3
Molecular Formula
C6H8O4
Molecular Weight
144.125 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point64-69 ºC
Boiling Point147 ºC (16 mmHg)
Density1.2±0.1 g/cm3
Flash Point109.6±16.1 °C
Exact Mass144.042252
PSA63.60000
LogP0.29
Vapor Pressure0.0±1.1 mmHg at 25°C
Refractive Index1.469

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Ausama Atwan, et al. Oral Fumaric Acid Esters for Psoriasis. Cochrane Database Syst Rev. 2015 Aug 10;2015(8):CD010497.

Customs & Trade Information

HS Code2918990090
Summary2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Monoethyl fumarate?

The CAS number of Monoethyl fumarate is 2459-05-4.

What are the molecular formula and molecular weight of Monoethyl fumarate?

Monoethyl fumarate has molecular formula C6H8O4 and molecular weight 144.125 g/mol.

Is Monoethyl fumarate hazardous?

Monoethyl fumarate has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Monoethyl fumarate?

For Monoethyl fumarate, Upstream Products: Monoethyl fumarate, Ethyl diazoacetate, Maleic anhydride; Downstream Products: Maleic anhydride, (E)-Ethyl 4-oxobut-2-enoate, Monoethyl succinate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Monoethyl fumarate (CAS 2459-05-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-44332-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.