9-Aminocamptothecin

Also known as: (20S)-9-Aminocamptothecin, (4S)-10-Amino-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, NSC 603071, 9-AC

9-Aminocamptothecin (CAS 91421-43-1) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C20H17N3O4 and a molecular weight of 363.367 g/mol. Key properties include a boiling point of 819.6±65.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 449.5±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 91421-43-1
Jingsj CID: J-43576-7
Molecular Formula: C₂₀H₁₇N₃O₄
Molecular Weight: 363.367 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	819.6±65.0 °C at 760 mmHg
Density	1.6±0.1 g/cm3
Flash Point	449.5±34.3 °C
Exact Mass	363.121918
PSA	107.44000
LogP	0.44
Vapor Pressure	0.0±3.1 mmHg at 25°C
Refractive Index	1.771
Storage Conditions	2-8°C

Activity & Biological Data

Target	Topoisomerase I
Additional Information	[1]. Li ML, et al. Pharmacological determinants of 9-aminocamptothecin cytotoxicity. Clin Cancer Res. 2001 Jan;7(1):168-74. [2]. de Souza PL, et al. 9-Aminocamptothecin: a topoisomerase I inhibitor with preclinical activity in prostate cancer. Clin Cancer Res. 1997 Feb;3(2):287-94. [3]. Jeha S, et al. Activity of oral and intravenous 9-aminocamptothecin in SCID mice engrafted with human leukemia. Leuk Lymphoma. 1998 Dec;32(1-2):159-64.

Target

Topoisomerase I

Additional Information

[1]. Li ML, et al. Pharmacological determinants of 9-aminocamptothecin cytotoxicity. Clin Cancer Res. 2001 Jan;7(1):168-74. [2]. de Souza PL, et al. 9-Aminocamptothecin: a topoisomerase I inhibitor with preclinical activity in prostate cancer. Clin Cancer Res. 1997 Feb;3(2):287-94. [3]. Jeha S, et al. Activity of oral and intravenous 9-aminocamptothecin in SCID mice engrafted with human leukemia. Leuk Lymphoma. 1998 Dec;32(1-2):159-64.

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 9-Aminocamptothecin?

The CAS number of 9-Aminocamptothecin is 91421-43-1.

What are the molecular formula and molecular weight of 9-Aminocamptothecin?

9-Aminocamptothecin has molecular formula C20H17N3O4 and molecular weight 363.367 g/mol.

What are the upstream and downstream products of 9-Aminocamptothecin?

For 9-Aminocamptothecin, Upstream Products: Rubitecan, Camptothecin, (S)-10-Hydroxycamptothecin; Downstream Products: 10-Hydroxycamptothecin, Camptothecin, 9-Methoxycamptothecin.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "9-Aminocamptothecin (CAS 91421-43-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-43576-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.