Rubitecan

Also known as: 9-Nitrocamptothecin, 9-Nitro-20(S)-camptothecin, 9-Nitro-CPT, RFS 2000, Orathecin, 9-Nitrocellulose camptothecine, (4S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Rubitecan (CAS 91421-42-0) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H15N3O6 and a molecular weight of 393.350 g/mol. Key properties include a melting point of 182-186ºC, a boiling point of 816.3±65.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 447.5±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 91421-42-0
Jingsj CID: J-1979666-8
Molecular Formula: C₂₀H₁₅N₃O₆
Molecular Weight: 393.350 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	182-186ºC
Boiling Point	816.3±65.0 °C at 760 mmHg
Density	1.6±0.1 g/cm3
Flash Point	447.5±34.3 °C
Exact Mass	393.096100
PSA	127.24000
LogP	1.38
Vapor Pressure	0.0±3.1 mmHg at 25°C
Refractive Index	1.762
Storage Conditions	Room temp

Activity & Biological Data

Target	Topoisomerase I[1]
Additional Information	[1]. Burris HA 3rd, et al. Phase II trial of oral rubitecan in previously treated pancreatic cancer patients. Oncologist. 2005 Mar;10(3):183-90. [2]. Rubitecan: 9-NC, 9-Nitro-20(S)-camptothecin, 9-nitro-camptothecin, 9-nitrocamptothecin, RFS 2000, RFS2000. Drugs R D. 2004;5(5):305-11. [3]. Rubitecan [4]. Xia M, et al. Identification of repurposed small molecule drugs for chordoma therapy. Cancer Biol Ther. 2013 Jul;14(7):638-47.

Target

Topoisomerase I[1]

Additional Information

[1]. Burris HA 3rd, et al. Phase II trial of oral rubitecan in previously treated pancreatic cancer patients. Oncologist. 2005 Mar;10(3):183-90. [2]. Rubitecan: 9-NC, 9-Nitro-20(S)-camptothecin, 9-nitro-camptothecin, 9-nitrocamptothecin, RFS 2000, RFS2000. Drugs R D. 2004;5(5):305-11. [3]. Rubitecan [4]. Xia M, et al. Identification of repurposed small molecule drugs for chordoma therapy. Cancer Biol Ther. 2013 Jul;14(7):638-47.

Frequently Asked Questions

What is the CAS number of Rubitecan?

The CAS number of Rubitecan is 91421-42-0.

What are the molecular formula and molecular weight of Rubitecan?

Rubitecan has molecular formula C20H15N3O6 and molecular weight 393.350 g/mol.

What are the upstream and downstream products of Rubitecan?

For Rubitecan, Upstream Products: Camptothecin, (S)-10-Hydroxycamptothecin, 9-Nitro-10-hydroxycamptothecin; Downstream Products: 9-Aminocamptothecin, Camptothecin, 10-Hydroxycamptothecin.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Rubitecan (CAS 91421-42-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1979666-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.