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2,2-Difluoroacetophenone

Also known as: 2,2-Difluoro-1-phenylethan-1-one, alpha,alpha-Difluoroacetophenone, Difluoromethyl phenyl ketone, Ethanone, 2,2-difluoro-1-phenyl-

2,2-Difluoroacetophenone (CAS 395-01-7) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C8H6F2O and a molecular weight of 156.12900 g/mol. Key properties include a melting point of 48-50ºC, a boiling point of 53-54ºC/12mm, a density of 1.18g/cm3 and a flash point of 71.9ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
395-01-7
Jingsj CID
J-43223-5
Molecular Formula
C8H6F2O
Molecular Weight
156.12900 g/mol
Category
Ketones
Last updated
8/21/2026

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Physicochemical Properties

Melting Point48-50ºC
Boiling Point53-54ºC/12mm
Density1.18g/cm3
Flash Point71.9ºC
Exact Mass156.03900
PSA17.07000
LogP2.13440
Refractive Index1.4955
Storage Conditions2-8°C

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation

Customs & Trade Information

HS Code2914700090
SummaryHS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 2,2-Difluoroacetophenone?

The CAS number of 2,2-Difluoroacetophenone is 395-01-7.

What are the molecular formula and molecular weight of 2,2-Difluoroacetophenone?

2,2-Difluoroacetophenone has molecular formula C8H6F2O and molecular weight 156.12900 g/mol.

Is 2,2-Difluoroacetophenone hazardous?

2,2-Difluoroacetophenone has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of 2,2-Difluoroacetophenone?

For 2,2-Difluoroacetophenone, Upstream Products: Difluoroacetonitrile, benzene, 2,2-Dichloroacetophenone; Downstream Products: (Difluoromethyl)benzene, 4-(Difluoromethyl)-1-fluorobenzene, 2,2-difluoro-1-phenylethanamine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2,2-Difluoroacetophenone (CAS 395-01-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-43223-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.