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2-Chloro-2,2-difluoroacetophenone

Also known as: 2-Chloro-2,2-difluoro-1-phenylethanone, alpha-Chloro-alpha,alpha-difluoroacetophenone, alpha,alpha-Difluorophenacyl chloride, Chlorodifluoroacetophenone, Chlorodifluoromethyl phenyl ketone

2-Chloro-2,2-difluoroacetophenone (CAS 384-67-8) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C8H5ClF2O and a molecular weight of 190.574 g/mol. Key properties include a boiling point of 199.1±35.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 74.2±25.9 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
384-67-8
Jingsj CID
J-36856-9
Molecular Formula
C8H5ClF2O
Molecular Weight
190.574 g/mol
Category
Ketones
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point199.1±35.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point74.2±25.9 °C
Exact Mass189.999695
PSA17.07000
LogP2.65
Vapor Pressure0.3±0.4 mmHg at 25°C
Refractive Index1.490

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2914700090
SummaryHS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 2-Chloro-2,2-difluoroacetophenone?

The CAS number of 2-Chloro-2,2-difluoroacetophenone is 384-67-8.

What are the molecular formula and molecular weight of 2-Chloro-2,2-difluoroacetophenone?

2-Chloro-2,2-difluoroacetophenone has molecular formula C8H5ClF2O and molecular weight 190.574 g/mol.

Is 2-Chloro-2,2-difluoroacetophenone hazardous?

2-Chloro-2,2-difluoroacetophenone has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 2-Chloro-2,2-difluoroacetophenone?

For 2-Chloro-2,2-difluoroacetophenone, Upstream Products: benzene, 2,2,2-trichloroacetophenone, Phenylmagnesium bromide; Downstream Products: 2,2-Difluoroacetophenone, (Difluoromethoxy)benzene, alpha-(Trifluoromethyl)styrene.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-Chloro-2,2-difluoroacetophenone (CAS 384-67-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-36856-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.