Alosetron

Also known as: 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido[4,3-b]indol-1-one, Lotronex, GR 68755, GR-68755, GR-68755X, GR68755, UNII-13Z9HTH115, 1H-Pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-

Alosetron (CAS 122852-42-0) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C17H18N4O and a molecular weight of 294.35100 g/mol. Key properties include a boiling point of 648.1ºC at 760 mmHg, a density of 1.34 g/cm3 and a flash point of 345.8ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 122852-42-0
Jingsj CID: J-40812-8
Molecular Formula: C₁₇H₁₈N₄O
Molecular Weight: 294.35100 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	648.1ºC at 760 mmHg
Density	1.34 g/cm3
Flash Point	345.8ºC
Exact Mass	294.14800
PSA	53.92000
LogP	2.34620
Vapor Pressure	1.1E-16mmHg at 25°C
Refractive Index	1.706
Storage Conditions	2-8℃

Activity & Biological Data

Additional Information	[1]. Alosetron: an effective treatment for diarrhea-predominant irritable bowel syndrome By Harris, Lucinda A.; Chang, Lin From Women's Health (2007), 3(1), 15-27. [2]. Cremonini F, Nicandro JP, Atkinson V, Shringarpure R, Chuang E, Lembo A. Randomised clinical trial: alosetron improves quality of life and reduces restriction of daily activities in women with severe diarrhoea-predominant IBS. Aliment Pharmacol Ther. 20 [3]. Lucak S. Irritable bowel syndrome and ischemic colitis: evidence supporting the increased use of alosetron. Therap Adv Gastroenterol. 2012 Jul;5(4):215-8. [4]. Nicandro JP, Shin P, Chuang E. Evaluation of treatment continuation with alosetron by IBS-D severity criteria. Curr Med Res Opin. 2012 Mar;28(3):449-56.

Additional Information

[1]. Alosetron: an effective treatment for diarrhea-predominant irritable bowel syndrome By Harris, Lucinda A.; Chang, Lin From Women's Health (2007), 3(1), 15-27. [2]. Cremonini F, Nicandro JP, Atkinson V, Shringarpure R, Chuang E, Lembo A. Randomised clinical trial: alosetron improves quality of life and reduces restriction of daily activities in women with severe diarrhoea-predominant IBS. Aliment Pharmacol Ther. 20 [3]. Lucak S. Irritable bowel syndrome and ischemic colitis: evidence supporting the increased use of alosetron. Therap Adv Gastroenterol. 2012 Jul;5(4):215-8. [4]. Nicandro JP, Shin P, Chuang E. Evaluation of treatment continuation with alosetron by IBS-D severity criteria. Curr Med Res Opin. 2012 Mar;28(3):449-56.

Frequently Asked Questions

What is the CAS number of Alosetron?

The CAS number of Alosetron is 122852-42-0.

What are the molecular formula and molecular weight of Alosetron?

Alosetron has molecular formula C17H18N4O and molecular weight 294.35100 g/mol.

What are the upstream and downstream products of Alosetron?

For Alosetron, Upstream Products: 4-(Chloromethyl)-5-methyl-1-(triphenylmethyl)-1H-imidazole, 2,3,4,5-Tetrahydro-5-methyl-1H-pyrido[4,3-b]indol-1-one, (4-Methyl-1H-imidazol-5-yl)methanol hydrochloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Alosetron (CAS 122852-42-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-40812-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.