Salinomycin

Also known as: Coxistac, Bio-cox, Antibiotic 61477, Salinomycin (acid)

Salinomycin (CAS 53003-10-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C42H70O11 and a molecular weight of 751.00 g/mol. Key properties include a melting point of 112.5-113.5 °C(lit.), a boiling point of 839.2±65.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 243.2±27.8 °C. It is classified under GHS with signal word Danger and hazard statements H300. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 53003-10-4
Jingsj CID: J-40748-3
Molecular Formula: C₄₂H₇₀O₁₁
Molecular Weight: 751.00 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	112.5-113.5 °C(lit.)
Boiling Point	839.2±65.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	243.2±27.8 °C
PSA	164.04000
LogP	6.10
Vapor Pressure	0.0±0.6 mmHg at 25°C
Refractive Index	1.547
Storage Conditions	2-8°C
Stability	Stable, but may be heat sensitive - keep cool. Incompatible with strong oxidizing agents.

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H300

Activity & Biological Data

Target	IC50: 163 nM (Wnt1-stimulated reporter)[1]
Additional Information	[1]. Lu D, et al. Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13253-7. [2]. Zhou J, et al. Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactiveoxygen species. Toxicol Lett. 2013 Oct 24;222(2):139-45. [3]. Wang F, et al. Salinomycin Inhibits Proliferation and Induces Apoptosis of Human Hepatocellular Carcinoma Cells In Vitro and In Vivo. PLoS One. 2012; 7(12): e50638. [4]. Qu H, et al. Effect of salinomycin on metastasis and invasion of bladder cancer cell line T24. Asian Pac J Trop Med. 2015 Jul;8(7):578-82.

Target

IC50: 163 nM (Wnt1-stimulated reporter)[1]

Additional Information

[1]. Lu D, et al. Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13253-7. [2]. Zhou J, et al. Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactiveoxygen species. Toxicol Lett. 2013 Oct 24;222(2):139-45. [3]. Wang F, et al. Salinomycin Inhibits Proliferation and Induces Apoptosis of Human Hepatocellular Carcinoma Cells In Vitro and In Vivo. PLoS One. 2012; 7(12): e50638. [4]. Qu H, et al. Effect of salinomycin on metastasis and invasion of bladder cancer cell line T24. Asian Pac J Trop Med. 2015 Jul;8(7):578-82.

Customs & Trade Information

HS Code	2309901000

Frequently Asked Questions

What is the CAS number of Salinomycin?

The CAS number of Salinomycin is 53003-10-4.

What are the molecular formula and molecular weight of Salinomycin?

Salinomycin has molecular formula C42H70O11 and molecular weight 751.00 g/mol.

Is Salinomycin hazardous?

Salinomycin has GHS signal word Danger and hazard statements H300.

What are the upstream and downstream products of Salinomycin?

For Salinomycin, Upstream Products: Salinomycin sodium salt.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Salinomycin (CAS 53003-10-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-40748-3 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.