Cytisine

Also known as: (-)-Cytisine, (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, (1R,5S)-3,4,5,6-Tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one, Baptitoxin, Baptitoxine, Cytisin, Cytiton, Cytitone, Laburnin, Sophorin, Sophorine, Tabex, Tsitafat, Ulexin, Ulexine, Lupinidine

Cytisine (CAS 485-35-8) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C11H14N2O and a molecular weight of 190.242 g/mol. Key properties include a melting point of 154-156ºC, a boiling point of 413.0±34.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 203.6±25.7 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 485-35-8
Jingsj CID: J-38508-4
Molecular Formula: C₁₁H₁₄N₂O
Molecular Weight: 190.242 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	154-156ºC
Boiling Point	413.0±34.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	203.6±25.7 °C
Exact Mass	190.110611
PSA	34.03000
LogP	0.07
Vapor Pressure	0.0±1.0 mmHg at 25°C
Refractive Index	1.623

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H301 — Toxic if swallowed
H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation

Activity & Biological Data

Target	α4β2 nAChRs[1].
Additional Information	[1]. Pabreza LA, et al. [3H]cytisine binding to nicotinic cholinergic receptors in brain. Mol Pharmacol. 1991 Jan;39(1):9-12. [2]. Grebenstein PE, et al. The effects of noncontingent and self-administered cytisine on body weight and meal patterns in male Sprague-Dawley rats. Pharmacol Biochem Behav. 2013 Sep;110:192-200. [3]. Walker N, et al. Cytisine versus nicotine for smoking cessation. N Engl J Med. 2014 Dec 18;371(25):2353-62. [4]. Yu L, et al. Cytisine induces endoplasmic reticulum stress caused by calcium overload in HepG2 cells. Oncol Rep. 2018 Mar;39(3):1475-1484.

Target

α4β2 nAChRs[1].

Additional Information

[1]. Pabreza LA, et al. [3H]cytisine binding to nicotinic cholinergic receptors in brain. Mol Pharmacol. 1991 Jan;39(1):9-12. [2]. Grebenstein PE, et al. The effects of noncontingent and self-administered cytisine on body weight and meal patterns in male Sprague-Dawley rats. Pharmacol Biochem Behav. 2013 Sep;110:192-200. [3]. Walker N, et al. Cytisine versus nicotine for smoking cessation. N Engl J Med. 2014 Dec 18;371(25):2353-62. [4]. Yu L, et al. Cytisine induces endoplasmic reticulum stress caused by calcium overload in HepG2 cells. Oncol Rep. 2018 Mar;39(3):1475-1484.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Cytisine?

The CAS number of Cytisine is 485-35-8.

What are the molecular formula and molecular weight of Cytisine?

Cytisine has molecular formula C11H14N2O and molecular weight 190.242 g/mol.

Is Cytisine hazardous?

Cytisine has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of Cytisine?

For Cytisine, Upstream Products: Cytisine; Downstream Products: Cytisine, N-Methylcytisine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Cytisine (CAS 485-35-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-38508-4 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.