1-methylisatin
Also known as: 1-methylindole-2,3-dione, 1-methyl-2,3-indolinedione, N-methylisatin, N-methylindoline-2,3-dione, 1-methyl-1H-indole-2,3-dione, 1-methylindolin-2,3-dione, 1-methyl-2,3-dihydro-1H-indole-2,3-dione, N-methylindol-2,3-dione, OL-57, NSC 42449, 1H-Indole-2,3-dione, 1-methyl-
1-methylisatin (CAS 2058-74-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C9H7NO2 and a molecular weight of 161.157 g/mol. Key properties include a melting point of 130-133 °C(lit.), a boiling point of 294.3±23.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 137.4±15.0 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H315 — Causes skin irritation and H318 — Causes serious eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 2058-74-4
- Jingsj CID
- J-3826-6
- Molecular Formula
- C9H7NO2
- Molecular Weight
- 161.157 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 130-133 °C(lit.) |
|---|---|
| Boiling Point | 294.3±23.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 137.4±15.0 °C |
| Exact Mass | 161.047684 |
| PSA | 37.38000 |
| LogP | 0.58 |
| Vapor Pressure | 0.0±0.6 mmHg at 25°C |
| Refractive Index | 1.607 |
GHS Safety & Compliance
- H301 — Toxic if swallowed
- H315 — Causes skin irritation
- H318 — Causes serious eye damage
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | hiCE:38.2 μM (Ki) hCE1:5.38 μM (Ki) |
|---|---|
| Additional Information | [1]. Hyatt JL, et al. Selective inhibition of carboxylesterases by isatins, indole-2,3-diones. J Med Chem. 2007 Apr 19;50(8):1876-85. [2]. Mandal P, et al. Fluorescence spectroscopic characterization of the interaction of human adult hemoglobin and two isatins, 1-methylisatin and 1-phenylisatin: a comparative study. J Phys Chem B. 2009 Nov 12;113(45):14904-13. |
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 1-methylisatin?
The CAS number of 1-methylisatin is 2058-74-4.
What are the molecular formula and molecular weight of 1-methylisatin?
1-methylisatin has molecular formula C9H7NO2 and molecular weight 161.157 g/mol.
Is 1-methylisatin hazardous?
1-methylisatin has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H315 — Causes skin irritation; H318 — Causes serious eye damage.
What are the upstream and downstream products of 1-methylisatin?
For 1-methylisatin, Upstream Products: 1-Methylindole, isatin, Dimethyl sulfate; Downstream Products: 1-Methyl-1H-indole-3-carboxylic acid, Allyl phenyl ether, Benzyl phenyl ether.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "1-methylisatin (CAS 2058-74-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-3826-6 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.