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Voriconazole

Also known as: Vfend, UK-109496, (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, (αR,βS)-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol, 2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

Voriconazole (CAS 137234-62-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H14F3N5O and a molecular weight of 349.31 g/mol. Key properties include a melting point of 127-130°C, a boiling point of 508.6±60.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 261.4±32.9 °C. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour, H301 — Toxic if swallowed and H311 — Toxic in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
137234-62-9
Jingsj CID
J-37936-2
Molecular Formula
C16H14F3N5O
Molecular Weight
349.31 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point127-130°C
Boiling Point508.6±60.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point261.4±32.9 °C
PSA76.72000
LogP0.93
Vapor Pressure0.0±1.4 mmHg at 25°C
Refractive Index1.617
Storage ConditionsStore at +4°C

GHS Safety & Compliance

Flammable / Acute Toxicity / Health HazardSignal word: Danger
  • H225 — Highly flammable liquid and vapour
  • H301 — Toxic if swallowed
  • H311 — Toxic in contact with skin
  • H331 — Toxic if inhaled
  • H370 — Causes damage to organs

Activity & Biological Data

Additional Information[1]. Mikus G, Scholz IM, Weiss J. Pharmacogenomics of the triazole antifungal agent voriconazole. Pharmacogenomics. 2011 Jun;12(6):861-72. doi: 10.2217/pgs.11.18. [2]. Scholz I, Oberwittler H, Riedel KD, et al. Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation to CYP2C19 genotype. Br J Clin Pharmacol. 2009 Dec;68(6):906-15. doi: 10.1111/j.1365-2125.2009.03534.x. [3]. Herbrecht R. Voriconazole: therapeutic review of a new azole antifungal. Expert Rev Anti Infect Ther. 2004 Aug;2(4):485-97. [4]. Louis D. Saravolatz, Section Editor, Leonard B. Johnson, et al. Voriconazole: A New Triazole Antifungal Agent. Clin Infect Dis. 2003,36 (5): 630-637. [5]. John R. Perfect, Kieren A. Marr, Thomas J. Walsh, et al. Voriconazole Treatment for Less-Common, Emerging, or Refractory Fungal Infections. Clin Infect Dis. 2003, 36 (9): 1122-1131.

Customs & Trade Information

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Voriconazole?

The CAS number of Voriconazole is 137234-62-9.

What are the molecular formula and molecular weight of Voriconazole?

Voriconazole has molecular formula C16H14F3N5O and molecular weight 349.31 g/mol.

Is Voriconazole hazardous?

Voriconazole has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H301 — Toxic if swallowed; H311 — Toxic in contact with skin.

What are the upstream and downstream products of Voriconazole?

For Voriconazole, Upstream Products: 4-Chloro-6-ethyl-5-fluoropyrimidine, 6-Ethyl-5-fluoropyrimidin-4(3H)-one, (2R,3S/2S,3R)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Voriconazole (CAS 137234-62-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-37936-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.