2-Chloro-2',4'-difluoroacetophenone
Also known as: 2-Chloro-1-(2,4-difluorophenyl)ethanone, 2,4-Difluorophenacyl chloride, Chloromethyl(2,4-difluorophenyl) ketone, Ethanone, 2-chloro-1-(2,4-difluorophenyl)-, 2',4'-Difluoro-α-chloroacetophenone, MFCD00013252
2-Chloro-2',4'-difluoroacetophenone (CAS 51336-94-8) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C8H5ClF2O and a molecular weight of 190.574 g/mol. Key properties include a melting point of 44-48 °C(lit.), a boiling point of 240.9±25.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 99.5±23.2 °C. It is classified under GHS with signal word Danger and hazard statements H314 — Causes severe skin burns and eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 51336-94-8
- Jingsj CID
- J-1524764-0
- Molecular Formula
- C8H5ClF2O
- Molecular Weight
- 190.574 g/mol
- Category
- Ketones
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 44-48 °C(lit.) |
|---|---|
| Boiling Point | 240.9±25.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 99.5±23.2 °C |
| Exact Mass | 189.999695 |
| PSA | 17.07000 |
| LogP | 1.57 |
| Vapor Pressure | 0.0±0.5 mmHg at 25°C |
| Refractive Index | 1.496 |
GHS Safety & Compliance
- H314 — Causes severe skin burns and eye damage
Customs & Trade Information
| HS Code | 2914700090 |
|---|---|
| Summary | HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of 2-Chloro-2',4'-difluoroacetophenone?
The CAS number of 2-Chloro-2',4'-difluoroacetophenone is 51336-94-8.
What are the molecular formula and molecular weight of 2-Chloro-2',4'-difluoroacetophenone?
2-Chloro-2',4'-difluoroacetophenone has molecular formula C8H5ClF2O and molecular weight 190.574 g/mol.
Is 2-Chloro-2',4'-difluoroacetophenone hazardous?
2-Chloro-2',4'-difluoroacetophenone has GHS signal word Danger and hazard statements H314 — Causes severe skin burns and eye damage.
What are the upstream and downstream products of 2-Chloro-2',4'-difluoroacetophenone?
For 2-Chloro-2',4'-difluoroacetophenone, Upstream Products: 1,3-Difluorobenzene, Chloroacetyl chloride, Chloroacetone; Downstream Products: 1-(2,4-Difluorophenyl)-2-hydroxyethanone, (R)-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol, Posaconazole.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "2-Chloro-2',4'-difluoroacetophenone (CAS 51336-94-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1524764-0 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.