Amlexanox

Also known as: AA-673, Amoxanox, Aphthasol, CHX-3673, Elics, Solfa, Amlexanoxum, 2-Amino-7-isopropyl-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid, 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid, MFCD00864790

Amlexanox (CAS 68302-57-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H14N2O4 and a molecular weight of 298.293 g/mol. Key properties include a melting point of >3000C, a boiling point of 570.0±50.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 298.5±30.1 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Nov 3, 2026.

CAS No.: 68302-57-8
Jingsj CID: J-35721-1
Molecular Formula: C₁₆H₁₄N₂O₄
Molecular Weight: 298.293 g/mol
Category: Organic Compounds
Last updated: 11/3/2026

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Physicochemical Properties

Melting Point	>3000C
Boiling Point	570.0±50.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	298.5±30.1 °C
Exact Mass	298.095367
PSA	106.42000
LogP	3.74
Vapor Pressure	0.0±1.6 mmHg at 25°C
Refractive Index	1.669
Storage Conditions	-20°C Freezer

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed

Activity & Biological Data

Target	IKKε:1-2 μM (IC50) TBK1:1-2 μM (IC50)
Additional Information	[1]. Reilly SM, et al. An inhibitor of the protein kinases TBK1 and IKK-e improves obesity-related metabolic dysfunctions in mice. Nat Med. 2013 Mar;19(3):313-21. [2]. Bell, J. AmLexanox for the treatment of recurrent aphthous ulcers. Clin Drug Investig, 2005. 25(9): p. 555-66. [3]. Zhang Y, et al. AmLexanox Suppresses Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss. Sci Rep. 2015 Sep 4;5:13575.

Target

IKKε:1-2 μM (IC50) TBK1:1-2 μM (IC50)

Additional Information

[1]. Reilly SM, et al. An inhibitor of the protein kinases TBK1 and IKK-e improves obesity-related metabolic dysfunctions in mice. Nat Med. 2013 Mar;19(3):313-21. [2]. Bell, J. AmLexanox for the treatment of recurrent aphthous ulcers. Clin Drug Investig, 2005. 25(9): p. 555-66. [3]. Zhang Y, et al. AmLexanox Suppresses Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss. Sci Rep. 2015 Sep 4;5:13575.

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Amlexanox?

The CAS number of Amlexanox is 68302-57-8.

What are the molecular formula and molecular weight of Amlexanox?

Amlexanox has molecular formula C16H14N2O4 and molecular weight 298.293 g/mol.

Is Amlexanox hazardous?

Amlexanox has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of Amlexanox?

For Amlexanox, Upstream Products: Ethyl 2-amino-7-isopropyl-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylate, 3-Cyano-6-isopropylchromone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 11/3/2026

How to cite: Jingsj. "Amlexanox (CAS 68302-57-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-35721-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.