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Propranolol hydrochloride

Also known as: Propranolol HCl, (±)-Propranolol hydrochloride, DL-Propranolol hydrochloride, (RS)-1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride, 1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride, Inderal hydrochloride

Propranolol hydrochloride (CAS 318-98-9) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C16H22ClNO2 and a molecular weight of 295.81000 g/mol. Key properties include a melting point of 163-165 °C(lit.), a boiling point of 434.9ºC at 760mmHg and a flash point of 216.8ºC. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Nov 2, 2026.

CAS No.
318-98-9
Jingsj CID
J-35586-2
Molecular Formula
C16H22ClNO2
Molecular Weight
295.81000 g/mol
Category
Organic Acids
Last updated
11/2/2026
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Physicochemical Properties

Melting Point163-165 °C(lit.)
Boiling Point434.9ºC at 760mmHg
Flash Point216.8ºC
Exact Mass331.110596
PSA41.49000
LogP3.77040
Storage Conditions2-8°C
Additional PropertySOLUBLE

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed

Activity & Biological Data

TargetIC50: 12 nM (βAR)[1]
Additional Information[1]. Briley M, et al. Evidence?against?beta-adrenoceptor?blocking?activity?of?diltiazem, a?drug?with?calcium?antagonistproperties. Br J Pharmacol.?1980 Aug;69(4):669-73. [2]. Munabi NC, et al. Propranolol Targets Hemangioma Stem Cells via cAMP and Mitogen-Activated Protein Kinase Regulation. Stem Cells Transl Med. 2016 Jan;5(1):45-55. [3]. Glennon RA, et al. The binding of propranolol at 5-hydroxytryptamine1D beta T355N mutant receptors may involve formation of two hydrogen bonds to asparagine. Mol Pharmacol. 1996 Jan;49(1):198-206. [4]. Horinouchi T, et al. Different changes of plasma membrane beta-adrenoceptors in rat heart after chronic administrationof propranolol, atenolol and bevantolol. Life Sci. 2007 Jul 12;81(5):399-404. Epub 2007 Jun 16.

Customs & Trade Information

HS Code2922509090
Summary2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Propranolol hydrochloride?

The CAS number of Propranolol hydrochloride is 318-98-9.

What are the molecular formula and molecular weight of Propranolol hydrochloride?

Propranolol hydrochloride has molecular formula C16H22ClNO2 and molecular weight 295.81000 g/mol.

Is Propranolol hydrochloride hazardous?

Propranolol hydrochloride has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of Propranolol hydrochloride?

For Propranolol hydrochloride, Upstream Products: Isopropylamine, 1-Naphthol, α-Naphthyl Glycidyl Ether; Downstream Products: (S)-Propranolol hydrochloride, Propranolol hydrochloride, 2,4-Dibromo-1-naphthol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Propranolol hydrochloride (CAS 318-98-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-35586-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.