Exemestane

Also known as: Aromasin, PNU155971, 6-Methylenandrosta-1,4-diene-3,17-dione, Exemestane (USP), FCE 24304, Androsta-1,4-diene-3,17-dione, 6-methylene-

Exemestane (CAS 107868-30-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H24O2 and a molecular weight of 296.403 g/mol. Key properties include a melting point of 155.13°C, a boiling point of 453.7±45.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 169.0±25.7 °C. It is classified under GHS with signal word Danger and hazard statements H319 — Causes serious eye irritation and H360 — May damage fertility or the unborn child. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 107868-30-4
Jingsj CID: J-35548-6
Molecular Formula: C₂₀H₂₄O₂
Molecular Weight: 296.403 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	155.13°C
Boiling Point	453.7±45.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	169.0±25.7 °C
Exact Mass	296.177643
PSA	34.14000
LogP	3.11
Vapor Pressure	0.0±1.1 mmHg at 25°C
Refractive Index	1.572

GHS Safety & Compliance

Irritant / Health HazardSignal word: Danger

H319 — Causes serious eye irritation
H360 — May damage fertility or the unborn child

Activity & Biological Data

Additional Information	[1]. Di Salle, E., et al., Novel aromatase and 5 alpha-reductase inhibitors. J Steroid Biochem Mol Biol, 1994. 49(4-6): p. 289-94. [2]. Miki, Y., et al., Effects of aromatase inhibitors on human osteoblast and osteoblast-like cells: a possible androgenic bone protective effects induced by exemestane. Bone, 2007. 40(4): p. 876-87. [3]. Wang, X. and S. Chen, Aromatase destabilizer: novel action of exemestane, a food and drug administration-approved aromatase inhibitor. Cancer Res, 2006. 66(21): p. 10281-6. [4]. Goss, P.E., et al., Effects of the steroidal aromatase inhibitor exemestane and the nonsteroidal aromatase inhibitor letrozole on bone and lipid metabolism in ovariectomized rats. Clin Cancer Res, 2004. 10(17): p. 5717-23. [5]. Zaccheo, T., D. Giudici, and E. Di Salle, Inhibitory effect of combined treatment with the aromatase inhibitor exemestane and tamoxifen on DMBA-induced mammary tumors in rats. J Steroid Biochem Mol Biol, 1993. 44(4-6): p. 677-80.

Additional Information

[1]. Di Salle, E., et al., Novel aromatase and 5 alpha-reductase inhibitors. J Steroid Biochem Mol Biol, 1994. 49(4-6): p. 289-94. [2]. Miki, Y., et al., Effects of aromatase inhibitors on human osteoblast and osteoblast-like cells: a possible androgenic bone protective effects induced by exemestane. Bone, 2007. 40(4): p. 876-87. [3]. Wang, X. and S. Chen, Aromatase destabilizer: novel action of exemestane, a food and drug administration-approved aromatase inhibitor. Cancer Res, 2006. 66(21): p. 10281-6. [4]. Goss, P.E., et al., Effects of the steroidal aromatase inhibitor exemestane and the nonsteroidal aromatase inhibitor letrozole on bone and lipid metabolism in ovariectomized rats. Clin Cancer Res, 2004. 10(17): p. 5717-23. [5]. Zaccheo, T., D. Giudici, and E. Di Salle, Inhibitory effect of combined treatment with the aromatase inhibitor exemestane and tamoxifen on DMBA-induced mammary tumors in rats. J Steroid Biochem Mol Biol, 1993. 44(4-6): p. 677-80.

Customs & Trade Information

HS Code	2937900090
Summary	HS: 2937900090 Tax rebate rate:9.0% Supervision conditions:q(report of inspection of soundness on import medicines) VAT:17.0% MFN tariff:4.0% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Exemestane?

The CAS number of Exemestane is 107868-30-4.

What are the molecular formula and molecular weight of Exemestane?

Exemestane has molecular formula C20H24O2 and molecular weight 296.403 g/mol.

Is Exemestane hazardous?

Exemestane has GHS signal word Danger and hazard statements H319 — Causes serious eye irritation; H360 — May damage fertility or the unborn child.

What are the upstream and downstream products of Exemestane?

For Exemestane, Upstream Products: 6-Methyleneandrost-4-ene-3,17-dione, Methylene boldenone, Carbon; Downstream Products: (8R,9S,10R,13S,14S)-10,13-Dimethylspiro[androsta-1,4-diene-6,2'-oxirane]-3,17-dione.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Exemestane (CAS 107868-30-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-35548-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.