Irinotecan

Also known as: CPT-11, Camptosar, Irinotecan (free base), DQ-2805, SN-38-11, (4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 1,4'-bipiperidine-1'-carboxylate, [1,4'-Bipiperidine]-1'-carboxylic acid (4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester

Irinotecan (CAS 97682-44-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C33H38N4O6 and a molecular weight of 586.678 g/mol. Key properties include a boiling point of 873.4±65.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 482.0±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 97682-44-5
Jingsj CID: J-35243-2
Molecular Formula: C₃₃H₃₈N₄O₆
Molecular Weight: 586.678 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	873.4±65.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	482.0±34.3 °C
Exact Mass	586.279114
PSA	114.20000
LogP	4.35
Vapor Pressure	0.0±0.3 mmHg at 25°C
Refractive Index	1.689
Storage Conditions	2-8°C

Activity & Biological Data

Target	Topoisomerase I
Additional Information	[1]. Morales C, et al. Antitumoral effect of irinotecan (CPT-11) on an experimental model of malignant neuroectodermal tumor. J Neurooncol. 2002 Feb;56(3):219-26. [2]. Pavillard V, et al. Determinants of the cytotoxicity of irinotecan in two human colorectal tumor cell lines. Cancer Chemother Pharmacol. 2002 Apr;49(4):329-35. Epub 2002 Jan 30. [3]. Allegrini G, et al. Thrombospondin-1 plus irinotecan: a novel antiangiogenic-chemotherapeutic combination that inhibits the growth of advanced human colon tumor xenografts in mice. Cancer Chemother Pharmacol. 2004 Mar;53(3):261-6. Epub 2003 Dec 5. [4]. Dela Cruz FS, et al. A case study of an integrative genomic and experimental therapeutic approach for rare tumors: identification of vulnerabilities in a pediatric poorly differentiated carcinoma. Genome Med. 2016 Oct 31;8(1):116. [5]. Huang MY, et al. Chemotherapeutic agent CPT-11 eliminates peritoneal resident macrophages by inducing apoptosis. Apoptosis. 2016 Feb;21(2):130-42.

Target

Topoisomerase I

Additional Information

[1]. Morales C, et al. Antitumoral effect of irinotecan (CPT-11) on an experimental model of malignant neuroectodermal tumor. J Neurooncol. 2002 Feb;56(3):219-26. [2]. Pavillard V, et al. Determinants of the cytotoxicity of irinotecan in two human colorectal tumor cell lines. Cancer Chemother Pharmacol. 2002 Apr;49(4):329-35. Epub 2002 Jan 30. [3]. Allegrini G, et al. Thrombospondin-1 plus irinotecan: a novel antiangiogenic-chemotherapeutic combination that inhibits the growth of advanced human colon tumor xenografts in mice. Cancer Chemother Pharmacol. 2004 Mar;53(3):261-6. Epub 2003 Dec 5. [4]. Dela Cruz FS, et al. A case study of an integrative genomic and experimental therapeutic approach for rare tumors: identification of vulnerabilities in a pediatric poorly differentiated carcinoma. Genome Med. 2016 Oct 31;8(1):116. [5]. Huang MY, et al. Chemotherapeutic agent CPT-11 eliminates peritoneal resident macrophages by inducing apoptosis. Apoptosis. 2016 Feb;21(2):130-42.

Frequently Asked Questions

What is the CAS number of Irinotecan?

The CAS number of Irinotecan is 97682-44-5.

What are the molecular formula and molecular weight of Irinotecan?

Irinotecan has molecular formula C33H38N4O6 and molecular weight 586.678 g/mol.

What are the upstream and downstream products of Irinotecan?

For Irinotecan, Upstream Products: 4-piperidin-1-ylpiperidine-1-carbonyl chloride, 7-Ethyl-10-hydroxycamptothecin, 4-Piperidinopiperidine; Downstream Products: 4-Piperidinopiperidine, 7-Ethyl-10-hydroxycamptothecin, Irinotecan hydrochloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Irinotecan (CAS 97682-44-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-35243-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.