Corticosterone
Also known as: (11β)-11,21-Dihydroxypregn-4-ene-3,20-dione, 11β,21-Dihydroxyprogesterone, Kendall's compound B, Reichstein's substance H, 4-Pregnene-11β,21-diol-3,20-dione, 17-Deoxycortisol
Corticosterone (CAS 50-22-6) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C21H30O4 and a molecular weight of 346.461 g/mol. Key properties include a melting point of 179-183 °C(lit.), a boiling point of 529.2±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 288.0±26.6 °C. It is classified under GHS with signal word Warning and hazard statements H317 — May cause an allergic skin reaction. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 50-22-6
- Jingsj CID
- J-33480-5
- Molecular Formula
- C21H30O4
- Molecular Weight
- 346.461 g/mol
- Category
- Ketones
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 179-183 °C(lit.) |
|---|---|
| Boiling Point | 529.2±50.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 288.0±26.6 °C |
| Exact Mass | 346.214417 |
| PSA | 74.60000 |
| LogP | 1.76 |
| Vapor Pressure | 0.0±3.2 mmHg at 25°C |
| Refractive Index | 1.576 |
| Stability | Stable, but light sensitive. Incompatible with strong oxidizing agents. |
GHS Safety & Compliance
- H317 — May cause an allergic skin reaction
Activity & Biological Data
| Target | Human Endogenous Metabolite |
|---|---|
| Additional Information | [1]. Gasser PJ, et al. Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: potential role for organiccation transporter 3 in stress-induced modulation of monoaminergic neurotransmission. J Neurosci. 2006 Aug 23;26(34):8758-8766. |
Frequently Asked Questions
What is the CAS number of Corticosterone?
The CAS number of Corticosterone is 50-22-6.
What are the molecular formula and molecular weight of Corticosterone?
Corticosterone has molecular formula C21H30O4 and molecular weight 346.461 g/mol.
Is Corticosterone hazardous?
Corticosterone has GHS signal word Warning and hazard statements H317 — May cause an allergic skin reaction.
What are the upstream and downstream products of Corticosterone?
For Corticosterone, Upstream Products: Hydrocortisone, Deoxycorticosterone, Corticosterone 21-acetate; Downstream Products: 4-Pregnene-3,11,20-trione, 5α-Dihydrocorticosterone, 11beta-Hydroxyprogesterone.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Corticosterone (CAS 50-22-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-33480-5 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.