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Chelidamic acid

Also known as: 4-Hydroxypyridine-2,6-dicarboxylic acid, 4-Oxo-1,4-dihydropyridine-2,6-dicarboxylic acid, 1,4-Dihydro-4-oxo-2,6-pyridinedicarboxylic acid, 4-Hydroxy-2,6-pyridinedicarboxylic acid, 2,6-Pyridinedicarboxylic acid, 4-hydroxy-, Chelidamic acid monohydrate, 4-Pyridone-2,6-dicarboxylic acid

Chelidamic acid (CAS 138-60-3) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C7H5NO5 and a molecular weight of 183.118 g/mol. Key properties include a melting point of 267 °C (dec.)(lit.), a boiling point of 428.3±45.0 °C at 760 mmHg, a density of 1.7±0.1 g/cm3 and a flash point of 212.8±28.7 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
138-60-3
Jingsj CID
J-33223-0
Molecular Formula
C7H5NO5
Molecular Weight
183.118 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point267 °C (dec.)(lit.)
Boiling Point428.3±45.0 °C at 760 mmHg
Density1.7±0.1 g/cm3
Flash Point212.8±28.7 °C
Exact Mass183.016769
PSA107.46000
LogP-1.43
Vapor Pressure0.0±2.2 mmHg at 25°C
Refractive Index1.635

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

TargetKi: 33 μM (Glutamate decarboxylase)[3].
Additional Information[1]. Searcey M, et al. Synthesis, DNA-cleaving properties and cytotoxicity of intercalating chelidamic acid derivatives. Anticancer Drug Des. 13(8):837-55. [2]. Espinet P, et al. Mesogenic palladium complexes with pincer ligands derived from dipicolinic acid. Inorg Chem. 2000 Aug, 7;39(16):3645-51. [3]. Porter TG, et al. Chelidonic acid and other conformationally restricted substrate analogues as inhibitors of rat brain glutamate decarboxylase. Biochem Pharmacol. 1985 Dec 1;34(23):4145-50.

Customs & Trade Information

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Chelidamic acid?

The CAS number of Chelidamic acid is 138-60-3.

What are the molecular formula and molecular weight of Chelidamic acid?

Chelidamic acid has molecular formula C7H5NO5 and molecular weight 183.118 g/mol.

Is Chelidamic acid hazardous?

Chelidamic acid has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Chelidamic acid?

For Chelidamic acid, Upstream Products: Chelidonic acid; Downstream Products: Diethyl 4-chloropyridine-2,6-dicarboxylate, 4-Chloropyridine-2,6-dicarboxylic acid, Dimethyl 4-chloropyridine-2,6-dicarboxylate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Chelidamic acid (CAS 138-60-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-33223-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.