3-(Methylthio)propionic acid

Also known as: 3-Methylthiopropionic acid, 3-Methylmercaptopropionic acid, 3-Methylsulfanylpropanoic acid, 4-Thiapentanoic acid, 3-Methylthiopropionate, Propanoic acid, 3-(methylthio)-, Propionic acid, 3-(methylthio)-, MFCD00059635

3-(Methylthio)propionic acid (CAS 646-01-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C4H8O2S and a molecular weight of 120.17 g/mol. Key properties include a melting point of 16ºC, a boiling point of 130ºC 2mm, a density of 1.16 and a flash point of 130°C/15mm. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 646-01-5
Jingsj CID: J-33011-0
Molecular Formula: C₄H₈O₂S
Molecular Weight: 120.17 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	16ºC
Boiling Point	130ºC 2mm
Density	1.16
Flash Point	130°C/15mm
PSA	52.32000
LogP	1.67190
Refractive Index	1.4884

Activity & Biological Data

Additional Information	[1]. Steele RD, et al. Identification of 3-methylthiopropionic acid as an intermediate in mammalian methioninemetabolism in vitro. J Biol Chem. 1978 Nov 10;253(21):7844-50. [2]. Surette R, et al. Formation of 3-methylthioacrylic acid from methionine by Streptomyces lincolnensis. Isolation of a peroxidase. J Antibiot (Tokyo). 1976 Jun;29(6):646-52. [3]. Kim YC, et al. 3-methylthiopropanoic acid produced by Enterobacter intermedium 60-2G inhibits fungal growth and weed seedling development. J Antibiot (Tokyo). 2003 Feb;56(2):177-80. [4]. Nakamura Y, et al. 3-Methylthiopropionic acid ethyl ester, isolated from Katsura-uri (Japanese pickling melon, Cucumis melo var. conomon), enhanced differentiation in human colon cancer cells. J Agric Food Chem. 2008 May 14;56(9):2977-84.

Additional Information

[1]. Steele RD, et al. Identification of 3-methylthiopropionic acid as an intermediate in mammalian methioninemetabolism in vitro. J Biol Chem. 1978 Nov 10;253(21):7844-50. [2]. Surette R, et al. Formation of 3-methylthioacrylic acid from methionine by Streptomyces lincolnensis. Isolation of a peroxidase. J Antibiot (Tokyo). 1976 Jun;29(6):646-52. [3]. Kim YC, et al. 3-methylthiopropanoic acid produced by Enterobacter intermedium 60-2G inhibits fungal growth and weed seedling development. J Antibiot (Tokyo). 2003 Feb;56(2):177-80. [4]. Nakamura Y, et al. 3-Methylthiopropionic acid ethyl ester, isolated from Katsura-uri (Japanese pickling melon, Cucumis melo var. conomon), enhanced differentiation in human colon cancer cells. J Agric Food Chem. 2008 May 14;56(9):2977-84.

Customs & Trade Information

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 3-(Methylthio)propionic acid?

The CAS number of 3-(Methylthio)propionic acid is 646-01-5.

What are the molecular formula and molecular weight of 3-(Methylthio)propionic acid?

3-(Methylthio)propionic acid has molecular formula C4H8O2S and molecular weight 120.17 g/mol.

What are the upstream and downstream products of 3-(Methylthio)propionic acid?

For 3-(Methylthio)propionic acid, Upstream Products: 3-Mercaptopropionic acid, iodomethane, Methyl 3-(methylthio)propionate; Downstream Products: Methanethiol, Dimethyl sulfide, 3,3'-Thiodipropionic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "3-(Methylthio)propionic acid (CAS 646-01-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-33011-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.