Dexamethasone
Also known as: (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Adexone, Aphthasolone, Auxiron, CALONAT, Corson, Decacort, Dexa, Dexa-Mamallet, Dexamethasone Base, Dexamonozon, Dexone, Dezone, DXM, Dxms, Hl-dex, mk125
Dexamethasone (CAS 50-02-2) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H29FO5 and a molecular weight of 392.461 g/mol. Key properties include a melting point of 255-264ºC, a boiling point of 568.2±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 297.5±30.1 °C. It is classified under GHS with signal word Danger and hazard statements H315 — Causes skin irritation, H317 — May cause an allergic skin reaction and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 50-02-2
- Jingsj CID
- J-31570-8
- Molecular Formula
- C22H29FO5
- Molecular Weight
- 392.461 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 255-264ºC |
|---|---|
| Boiling Point | 568.2±50.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 297.5±30.1 °C |
| Exact Mass | 392.199890 |
| PSA | 94.83000 |
| LogP | 1.87 |
| Vapor Pressure | 0.0±3.5 mmHg at 25°C |
| Refractive Index | 1.592 |
| Storage Conditions | 2~8°C |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H317 — May cause an allergic skin reaction
- H319 — Causes serious eye irritation
- H334 — May cause allergy or asthma symptoms if inhaled
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | Glucocorticoid receptor[1] |
|---|---|
| Additional Information | [1]. LaLone CA, et al. Effects of a glucocorticoid receptor agonist, Dexamethasone, on fathead minnow reproduction, growth, and development. Environ Toxicol Chem. 2012 Mar;31(3):611-22. [2]. Adcock IM, et al. Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: preferential targetting of NF-kappaB and lack of I-kappaB involvement. Br J Pharmacol. 1999 Jun;127(4):1003-11 [3]. Rocksén D, et al. Differential anti-inflammatory and anti-oxidative effects of Dexamethasone and N-acetylcysteine in endotoxin-induced lung inflammation. Clin Exp Immunol. 2000 Nov;122(2):249-56 [4]. Roussel D, et al. Dexamethasone treatment specifically increases the basal proton conductance of rat liver mitochondria. FEBS Lett. 2003 Apr 24;541(1-3):75-9. [5]. Maher HM, et al. Simultaneous determination of selected tyrosine kinase inhibitors with corticosteroids and antiemetics in rat plasma by solid phase extraction and ultra-performance liquid chromatography-tandem mass spectrometry: Application to pharmacokinetic interaction studies. J Pharm Biomed Anal. 2016 May 30;124:216-27. |
Customs & Trade Information
| HS Code | 2937210000 |
|---|
Frequently Asked Questions
What is the CAS number of Dexamethasone?
The CAS number of Dexamethasone is 50-02-2.
What are the molecular formula and molecular weight of Dexamethasone?
Dexamethasone has molecular formula C22H29FO5 and molecular weight 392.461 g/mol.
Is Dexamethasone hazardous?
Dexamethasone has GHS signal word Danger and hazard statements H315 — Causes skin irritation; H317 — May cause an allergic skin reaction; H319 — Causes serious eye irritation.
What are the upstream and downstream products of Dexamethasone?
For Dexamethasone, Upstream Products: Dexamethasone acetate; Downstream Products: Desoximetasone, Dexamethasone Phosphate.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Dexamethasone (CAS 50-02-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-31570-8 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.